Evidence map›Paper›PMID 38725930›Full record

ArticleClinical case reports2024

Eculizumab for paroxysmal nocturnal hemoglobinuria: Two cases of successful pregnancy outcomes.

Jovanka Ilic, Borislava Pujic, Branislava Jakovljevic, Borivoj Sekulic, Danijela Agic, Amir El Farra, Branimir Micanovic, Tihomir Vejnovic, Ivana Urosevic, Aleksandar Savic

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jovanka IlicClinic оf Hematology Clinical Center оf Vojvodina Novi Sad Serbia.ORCID https://orcid.org/0009-0000-3001-8664
Borislava PujicClinic of Anesthesia Intensive Care and Pain Therapy, Clinical Center оf Vojvodina Novi Sad Serbia.
Branislava JakovljevicClinic of Gynecology and Obstetrics Clinical Center оf Vojvodina Novi Sad Serbia.
Borivoj SekulicClinic оf Hematology Clinical Center оf Vojvodina Novi Sad Serbia.
Danijela AgicClinic оf Hematology Clinical Center оf Vojvodina Novi Sad Serbia.
Amir El FarraClinic оf Hematology Clinical Center оf Vojvodina Novi Sad Serbia.
Branimir MicanovicClinic оf Hematology Clinical Center оf Vojvodina Novi Sad Serbia.
Tihomir VejnovicClinic of Gynecology and Obstetrics Clinical Center оf Vojvodina Novi Sad Serbia.
Ivana UrosevicClinic оf Hematology Clinical Center оf Vojvodina Novi Sad Serbia.ORCID https://orcid.org/0000-0003-0672-3739
Aleksandar SavicClinic оf Hematology Clinical Center оf Vojvodina Novi Sad Serbia.ORCID https://orcid.org/0000-0002-5619-3724

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paroxysmal nocturnal hemoglobinuria is a rare disease with the incidence ranging from 0.08 to 0.57 per 100,000 person-years. Up to 25% of cases in women are detected during pregnancy. We report two cases of successful pregnancy outcomes in patients treated with eculizumab, pointing out the importance of interdisciplinary approach in these high-risk pregnancies.

Indexed as

eculizumabparoxysmal nocturnal hemoglobinuriaPNHpregnancy

Identifiers

PMID38725930
PMCPMC11079538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.