Evidence map›Paper›PMID 38725678›Full record

ReviewFrontiers in microbiology2024

Novel antiviral approaches for Marburg: a promising therapeutics in the pipeline.

Shriyansh Srivastava, Sachin Kumar, Sumel Ashique, Sathvik Belagodu Sridhar, Javedh Shareef, Sabin Thomas

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shriyansh SrivastavaDepartment of Pharmacology, Delhi Pharmaceutical Sciences and Research University (DPSRU), New Delhi, India.
Sachin KumarDepartment of Pharmacology, Delhi Pharmaceutical Sciences and Research University (DPSRU), New Delhi, India.
Sumel AshiqueDepartment of Pharmaceutical Sciences, Bengal College of Pharmaceutical Sciences & Research, Durgapur, West Bengal, India.
Sathvik Belagodu SridharRAK College of Pharmacy, RAK Medical & Health Sciences University, Ras al Khaimah, United Arab Emirates.
Javedh ShareefClinical Pharmacy & Pharmacology, RAK College of Pharmacy, RAK Medical & Health Sciences University, Ras al Khaimah, United Arab Emirates.
Sabin ThomasCollege of Health Sciences, University of Nizwa, Nizwa, Oman.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marburg virus disease (MVD) presents a significant global health threat, lacking effective antivirals and with current supportive care offering limited therapeutic options. This mini review explores the emerging landscape of novel antiviral strategies against MVD, focusing on promising therapeutics currently in the development pipeline. We delve into direct-acting antiviral approaches, including small molecule inhibitors targeting viral entry, replication, and assembly, alongside nucleic acid antisense and RNA interference strategies. Host-targeting antivirals are also considered, encompassing immune modulators like interferons and cytokine/chemokine modulators, broad-spectrum antivirals, and convalescent plasma and antibody-based therapies. The paper then examines preclinical and clinical development for the novel therapeutics, highlighting

Indexed as

antiviral therapyclinical trialscombination therapydrug resistanceimmune modulatorsMarburg virus diseaseRNA interferencesmall molecule inhibitors

Identifiers

PMID38725678
PMCPMC11079314

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.