Evidence map›Paper›PMID 38725666›Full record

ReviewFrontiers in pharmacology2024

Black phosphorus, an advanced versatile nanoparticles of antitumor, antibacterial and bone regeneration for OS therapy.

Lihui Sun, Yu Han, Yao Zhao, Jing Cui, Zhiguo Bi, Shiyu Liao, Zheru Ma, Fengxiang Lou, Chunsheng Xiao, Wei Feng and 3 more

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lihui SunDivision of Bone and Joint Surgery, Center of Orthopedics, First Hospital of Jilin University Changchun, Changchun, China.
Yu HanDivision of Bone and Joint Surgery, Center of Orthopedics, First Hospital of Jilin University Changchun, Changchun, China.
Yao ZhaoDivision of Bone and Joint Surgery, Center of Orthopedics, First Hospital of Jilin University Changchun, Changchun, China.
Jing CuiJilin Provincial Key Laboratory of Oral Biomedical Engineering, School and Hospital of Stomatology, Jilin University, Changchun, China.
Zhiguo BiDivision of Bone and Joint Surgery, Center of Orthopedics, First Hospital of Jilin University Changchun, Changchun, China.
Shiyu LiaoDivision of Bone and Joint Surgery, Center of Orthopedics, First Hospital of Jilin University Changchun, Changchun, China.
Zheru MaDivision of Bone and Joint Surgery, Center of Orthopedics, First Hospital of Jilin University Changchun, Changchun, China.
Fengxiang LouDepartment of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, China.
Chunsheng XiaoKey Laboratory of Polymer Eco-materials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China.
Wei FengDivision of Bone and Joint Surgery, Center of Orthopedics, First Hospital of Jilin University Changchun, Changchun, China.
Jianguo LiuDivision of Bone and Joint Surgery, Center of Orthopedics, First Hospital of Jilin University Changchun, Changchun, China.
Bo CaiDepartment of Diagnostic Ultrasound of People's Liberation Army 964 Hospital, Changchun, China.
Dongsong LiDivision of Bone and Joint Surgery, Center of Orthopedics, First Hospital of Jilin University Changchun, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OS) is the most common primary malignant bone tumor. In the clinic, usual strategies for OS treatment include surgery, chemotherapy, and radiation. However, all of these therapies have complications that cannot be ignored. Therefore, the search for better OS treatments is urgent. Black phosphorus (BP), a rising star of 2D inorganic nanoparticles, has shown excellent results in OS therapy due to its outstanding photothermal, photodynamic, biodegradable and biocompatible properties. This review aims to present current advances in the use of BP nanoparticles in OS therapy, including the synthesis of BP nanoparticles, properties of BP nanoparticles, types of BP nanoparticles, and modification strategies for BP nanoparticles. In addition, we have discussed comprehensively the application of BP in OS therapy, including single, dual, and multimodal synergistic OS therapies, as well as studies about bone regeneration and antibacterial properties. Finally, we have summarized the conclusions, limitations and perspectives of BP nanoparticles for OS therapy.

Indexed as

black phosphorusbone tissue engineeringnanomaterialsnanomedicineOS therapyversatile therapeutic strategies

Identifiers

PMID38725666
PMCPMC11079190

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.