Evidence map›Paper›PMID 38725618›Full record

ReviewFrontiers in oncology2024

Metastatic organotropism: a brief overview.

Margarida Carrolo, João A I Miranda, Guilherme Vilhais, António Quintela, Mário Fontes E Sousa, Diogo Alpuim Costa, Francisco R Pinto

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Spatial architecture of development and disease.Nature reviews. Genetics · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Molecular principles underlying aggressive cancers.Signal transduction and targeted therapy · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Deciphering organotropism reveals therapeutic targets in metastasis.Frontiers in cell and developmental biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Margarida Carrolo *Hematology and Oncology Department, CUF Oncologia, Lisbon, Portugal.
João A I Miranda *BioISI - Institute for Biosystems and Integrative Sciences, Faculty of Sciences, University of Lisbon, Lisbon, Portugal.
Guilherme VilhaisHematology and Oncology Department, CUF Oncologia, Lisbon, Portugal.
António QuintelaHematology and Oncology Department, CUF Oncologia, Lisbon, Portugal.
Mário Fontes E SousaHematology and Oncology Department, CUF Oncologia, Lisbon, Portugal.
Diogo Alpuim CostaHematology and Oncology Department, CUF Oncologia, Lisbon, Portugal.
Francisco R PintoBioISI - Institute for Biosystems and Integrative Sciences, Faculty of Sciences, University of Lisbon, Lisbon, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organotropism has been known since 1889, yet this vital component of metastasis has predominantly stayed elusive. This mini-review gives an overview of the current understanding of the underlying mechanisms of organotropism and metastases development by focusing on the formation of the pre-metastatic niche, immune defenses against metastases, and genomic alterations associated with organotropism. The particular case of brain metastases is also addressed, as well as the impact of organotropism in cancer therapy. The limited comprehension of the factors behind organotropism underscores the necessity for efficient strategies and treatments to manage metastases.

Indexed as

brain metastasisimmune response to metastasismetastasisorganotropismpre-metastatic niche

Identifiers

PMID38725618
PMCPMC11079203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.