Evidence map›Paper›PMID 38725185›Full record

Observational studyActa obstetricia et gynecologica Scandinavica2024

Glycemic control assessed by continuous glucose monitoring during pregnancy in women with type 1 diabetes and its association with preeclampsia, an observational Swedish cohort study.

Linda Englund Ögge, Annika Dotevall, Anders Elfvin, Ulrika Sandgren, Karolina Linden, Linnea Bohlin, Bernadette Wallstersson, Mårten Sjödell, Jaine Augustinsson, Anna Hagman

Abstract readObservational Study
In one paragraph

Observational study in Acta obstetricia et gynecologica Scandinavica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Glycaemic Control in Women With Type 1 Diabetes and Preeclampsia Risk: A Nationwide Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2026
    Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Linda Englund ÖggeDepartment of Obstetrics and Gynecology, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden.ORCID 0000-0001-8334-2070
Annika DotevallDepartment of Medicine, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden.
Anders ElfvinDepartment of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ulrika SandgrenDepartment of Obstetrics and Gynecology, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden.
Karolina LindenInstitute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-2792-3142
Linnea BohlinRegionhälsan Health Care, Gynecology and Obstetrics Clinic, Gothenburg, Sweden.
Bernadette WallsterssonDepartment of Obstetrics and Gynecology, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden.
Mårten SjödellDepartment of Obstetrics and Gynecology, Skaraborg Hospital, Skövde, Sweden.
Jaine AugustinssonRegionhälsan Health Care, Gynecology and Obstetrics Clinic, Gothenburg, Sweden.
Anna HagmanRegionhälsan Health Care, Gynecology and Obstetrics Clinic, Gothenburg, Sweden.

Funding

FoU Research Unit
6 · The paper itself

Abstract

introductionWomen with type 1 diabetes have an increased risk of preeclampsia (PE), but it is not fully understood if degree of glycemic control is associated with this risk. The aim of this study was to assess glycemic control during pregnancy analyzed by continuous glucose monitoring (CGM) in women with and without PE and to investigate if glycemic control is associated with increased risk of PE. MATERIAL AND

methodsA total of 120 pregnant Swedish women with type 1 diabetes using CGM were included. Background factors and pregnancy outcomes were collected from medical records. CGM data were collected via the internet-based platform Diasend. Mean glucose, standard deviation of mean glucose, percentage of time in target, time below target, and time above target were presented for each trimester in women who did or did not develop PE. Associations between CGM-derived metrics and PE were analyzed with logistic regression and adjusted for confounders.

resultsTwenty-two women (18.3%) developed PE. There were no significant differences in maternal characteristics between women with and without PE. Glycemic control improved in each trimester but was suboptimal in both groups. Time in target increased from 59% in the non-PE group and 54% in the PE group in the first trimester to 65% in both groups in the third trimester. There were no significant associations between glycemic control and PE after adjustment for confounders.

conclusionsDegree of glycemic control during pregnancy assessed by CGM was not associated with development of PE in women with type 1 diabetes. However, more research is needed to understand the role of glycemic control in relation to development of PE.

Indexed as

Blood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 1Glycemic ControlPre-EclampsiaPregnancy in DiabeticsAdultCohort StudiesContinuous Glucose MonitoringFemaleHumansPregnancySwedenBlood Glucosecontinuous glucose monitoringglycemic controllarge for gestational agepreeclampsiapregnancypreterm deliverytime above targettime below targettime in targettype 1 diabetes

Identifiers

PMID38725185
PMCPMC11168267

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.