ReviewAnesthesia and pain medicine2024
Use of vasopressors to manage spinal anesthesia-induced hypotension during cesarean delivery.
Review in Anesthesia and pain medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07384455 (Comparıson of the effectıveness of ephedrıne and norepınephrıne ın the Treatment of hypotensıon developıng ın spınal anaesthesıa durıng Caesarean sectıon surgerıes), which is not on this map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Comparıson of the effectıveness of ephedrıne and norepınephrıne ın the Treatment of hypotensıon developıng ın spınal anaesthesıa durıng Caesarean sectıon surgerıes
Who cites it
13 citing papers in PubMed.
- Fluid responsiveness-guided individualized strategy for preventing hypotension after spinal anesthesia in cesarean delivery: a randomized trial of prehydration versus norepinephrine preinfusion.BMC anesthesiology · 2026Trial
- Ultrasound image-based paravertebral nerve block combined with general anesthesia in laparoscopic radical resection of esophageal cancer : Paravertebral nerve block versus general anesthesia in the treatment of esophageal cancer: a randomized controlled trial.World journal of surgical oncology · 2025Trial
- Balancing haemodynamics in high-risk obstetrics: Spinal anaesthesia for emergency caesarean section in a parturient with uncorrected patent ductus arteriosus and severe anaemia.Indian journal of anaesthesia · 2026Article
- From visibility to influence.Anesthesia and pain medicine · 2026Article
- Prevalence, factors associated, and adverse maternal outcomes of spinal induced hypotension among mothers undergoing caesarean section at a tertiary hospital South-Western Uganda.BMC anesthesiology · 2026Article
- Article
- Prevention of post-spinal hypotension in high risk cesarean delivery: A systematic review and updated network meta-analysis of prophylactic vasopressor infusions.Indian journal of anaesthesia · 2026Article
- Managing spinal anesthesia-induced hypotension in cesarean section: emerging techniques and evidence-based strategies - a narrative review.Annals of medicine and surgery (2012) · 2025Review
- Review
- Dissecting Vasopressor Efficacy in the Management of Maternal Hypotension in Preeclamptic Cesarean Delivery: A Systematic Review of Randomized Controlled Trials.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2025Article
- A Retrospective Observational Study of Ephedrine Use in Hip Arthroplasty: Routine Practice at a Secondary Care Hospital in Romania.Clinics and practice · 2025Article
- Comparison of phenylephrine, ephedrine, and norepinephrine for the prevention and treatment of spinal-induced hypotension in pre-eclamptic patients undergoing caesarean section: A systematic review and network meta-analysis.Indian journal of anaesthesia · 2025Article
- Effect of preoperative oxytocin infusion on haemodynamics among women undergoing elective caesarean section under spinal anaesthesia: A randomised controlled study.Indian journal of anaesthesia · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cesarean sections are commonly performed under spinal anesthesia, which can lead to hypotension, adversely affecting maternal and fetal outcomes. Hypotension following spinal anesthesia is generally defined as a blood pressure of 80-90% below the baseline value. Various strategies have been implemented to reduce the incidence of spinal anesthesia-induced hypotension. The administration of vasopressors is a crucial method for preventing and treating hypotension. In the past decade, phenylephrine, a primarily alpha-adrenergic agonist, has been the preferred vasopressor for cesarean sections. Recently, norepinephrine, a potent alpha-agonist with modest beta-agonist activity, has gained popularity owing to its advantages over phenylephrine. Vasopressors can be administered via a bolus or continuous infusion. Although administering boluses alone is simpler in a clinical setting, continuous prophylactic infusion initiated immediately after spinal anesthesia is more effective in reducing the incidence of hypotension. Tailoring the infusion dose based on the patient's body weight and adjusting the rate in response to blood pressure changes, in addition to using a prophylactic or rescue bolus, helps reduce blood pressure variability during cesarean sections under spinal anesthesia until neonatal delivery.
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