Evidence map›Paper›PMID 38724994›Full record

ArticleBMC veterinary research2024

Characterization and pharmacokinetics of cinnamon and star anise compound essential oil pellets prepared via centrifugal granulation technology.

Dandan Yi, Wei Xu, Lanqian Qin, Yifei Xiang, Yihao Mo, Xia Liu, Yu Liu, Jianbo Peng, Zhengmin Liang, Jiakang He

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dandan Yi *College of Animal Science and Technology, Guangxi University, 100 Daxue Road, Xixiangtang District, Nanning, 530004, Guangxi, P. R. China.
Wei Xu *College of Animal Science and Technology, Guangxi University, 100 Daxue Road, Xixiangtang District, Nanning, 530004, Guangxi, P. R. China.
Lanqian QinCollege of Animal Science and Technology, Guangxi University, 100 Daxue Road, Xixiangtang District, Nanning, 530004, Guangxi, P. R. China.
Yifei XiangCollege of Animal Science and Technology, Guangxi University, 100 Daxue Road, Xixiangtang District, Nanning, 530004, Guangxi, P. R. China.
Yihao MoCollege of Animal Science and Technology, Guangxi University, 100 Daxue Road, Xixiangtang District, Nanning, 530004, Guangxi, P. R. China.
Xia LiuCollege of Animal Science and Technology, Guangxi University, 100 Daxue Road, Xixiangtang District, Nanning, 530004, Guangxi, P. R. China.
Yu LiuCollege of Animal Science and Technology, Guangxi University, 100 Daxue Road, Xixiangtang District, Nanning, 530004, Guangxi, P. R. China.
Jianbo PengGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, Nanning, 530004, PR China.
Zhengmin LiangCollege of Animal Science and Technology, Guangxi University, 100 Daxue Road, Xixiangtang District, Nanning, 530004, Guangxi, P. R. China.
Jiakang HeCollege of Animal Science and Technology, Guangxi University, 100 Daxue Road, Xixiangtang District, Nanning, 530004, Guangxi, P. R. China. jkhe@gxu.edu.cn.

Funding

National Natural Science Foundation of China 31960717
6 · The paper itself

Abstract

Cinnamon and star anise essential oils are extracted from natural plants and provide a theoretical basis for the development and clinical application of compound essential oil pellets. However, cinnamon oil and star anise oil have the characteristics of a pungent taste, extreme volatility, poor palatability, and unstable physical and chemical properties, which limit their clinical use in veterinary medicine. In this study, the inhibitory effects of cinnamon oil and star anise oil on Escherichia coli and Salmonella were measured. Compound essential oil pellets were successfully prepared by centrifugal granulation technology. Subsequently, the in vitro dissolution of the pellets and their pharmacokinetics in pigs were investigated. The results showd that, cinnamon and star anise oils showed synergistic or additive inhibitiory effects on Escherichia coli and Salmonella. The oil pellets had enteric characteristics in vitro and high dissolution in vitro. The pharmacokinetic results showed that the pharmacokinetic parameters Cmax and AUC were directly correlated with the dosage and showed linear pharmacokinetic characteristics, which provided a theoretical basis for the development and clinical application of compound essential oil pellets.

Indexed as

Cinnamomum zeylanicumEscherichia coliOils, VolatileAnimalsAnti-Bacterial AgentsCentrifugationMalePlant OilsSalmonellaSaturejaSwineAnti-Bacterial AgentsOils, VolatilePlant OilsAntibacterialCompound essential oil pelletsEntericPharmacokinetics

Identifiers

PMID38724994
PMCPMC11083769

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.