Evidence map›Paper›PMID 38724944›Full record

ArticleBMC pediatrics2024

Automated segmentation and volume prediction in pediatric Wilms' tumor CT using nnu-net.

Weikang Li, Yiran Sun, Guoxun Zhang, Qing Yang, Bo Wang, Xiaohui Ma, Hongxi Zhang

Abstract read
In one paragraph

Article in BMC pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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  6. Exploring theFrontiers in physiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Weikang Li *Department of Radiology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, No. 3333, Binshneg Rd, Hangzhou, China.
Yiran Sun *Wenzhou Medical University, Wenzhou, China.
Guoxun ZhangDepartment of Radiology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, No. 3333, Binshneg Rd, Hangzhou, China.
Qing YangDepartment of Radiology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, No. 3333, Binshneg Rd, Hangzhou, China.
Bo WangDepartment of Radiology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, No. 3333, Binshneg Rd, Hangzhou, China.
Xiaohui MaDepartment of Radiology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, No. 3333, Binshneg Rd, Hangzhou, China. rudra@zju.edu.cn.
Hongxi ZhangDepartment of Radiology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, No. 3333, Binshneg Rd, Hangzhou, China. hongxizhang11@zju.edu.cn.

Funding

National Key Research and Development Program of China 2023YFC2706100National Natural Science Foundation of China 82373971Natural Science Foundation of Zhejiang Province No.LY24H180002
6 · The paper itself

Abstract

backgroundRadiologic volumetric evaluation of Wilms' tumor (WT) is an important indicator to guide treatment decisions. However, due to the heterogeneity of the tumors, radiologists have main-guard differences in diagnosis that can lead to misdiagnosis and poor treatment. The aim of this study was to explore whether CT-based outlining of WT foci can be automated using deep learning.

methodsWe included CT intravenous phase images of 105 patients with WT and double-blind outlining of lesions by two radiologists. Then, we trained an automatic segmentation model using nnUnet. The Dice similarity coefficient (DSC) and 95th percentile Hausdorff distance (HD

resultsThe DSC and HD

conclusionWe introduce a novel method that enhances the accuracy of predicting WT volume by integrating AI automated outlining and 3D tumor diameters. This approach surpasses the accuracy of using AI outcomes alone and has the potential to enhance the clinical evaluation of pediatric patients with WT. By intertwining AI outcomes with clinical data, this method becomes more interpretive and offers promising applications beyond Wilms tumor, extending to other pediatric diseases.

Indexed as

Kidney NeoplasmsTomography, X-Ray ComputedWilms TumorChildChild, PreschoolDeep LearningDouble-Blind MethodFemaleHumansImaging, Three-DimensionalInfantMaleRetrospective StudiesTumor BurdenCTDeep learningWilms’ Tumor

Identifiers

PMID38724944
PMCPMC11080230

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.