Evidence map›Paper›PMID 38724872›Full record

ArticleIn vitro cellular & developmental biology. Animal2024

Characteristics of nuclear architectural abnormalities of myotubes differentiated from Lmna

Eiji Wada, Nao Susumu, Motoshi Kaya, Yukiko K Hayashi

Abstract read
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In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eiji WadaDepartment of Pathophysiology, Tokyo Medical University, Tokyo, Japan.
Nao SusumuDepartment of Pathophysiology, Tokyo Medical University, Tokyo, Japan.
Motoshi KayaDepartment of Physics, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Yukiko K HayashiDepartment of Pathophysiology, Tokyo Medical University, Tokyo, Japan. yhayashi@tokyo-med.ac.jp.

Funding

Acceleration Program for Intractable Disease Research Utilizing Disease-specific iPS cells 17935395Follow-up Grant from Tokyo Medical University 2022Grants-in-Aid for Scientific Research (B) from the Japanese Ministry of Education, Culture, Sports, Science and Technology 20H03594Intramural Research Grant for Neurological and Psychiatric Disorders of NCNP 2-5Intramural Research Grant for Neurological and Psychiatric Disorders of NCNP 29-4Intramural Research Grant for Neurological and Psychiatric Disorders of NCNP 5-6Practical Research Project for Rare/Intractable Diseases from the Japan Agency for Medical Research and Development 23809381
6 · The paper itself

Abstract

The presence of nuclear architectural abnormalities is a hallmark of the nuclear envelopathies, which are a group of diseases caused by mutations in genes encoding nuclear envelope proteins. Mutations in the lamin A/C gene cause several diseases, named laminopathies, including muscular dystrophies, progeria syndromes, and lipodystrophy. A mouse model carrying with the Lmna

Indexed as

Cell DifferentiationCell NucleusLamin Type AMuscle Fibers, SkeletalAnimalsCell ProliferationMiceMuscle, SkeletalMyoblastsNuclear ProteinsLamin Type ALmna protein, mouseNuclear ProteinsDNA damageEmery-Dreifuss muscular dystrophyLamin a/cNuclear deformationSkeletal muscle

Identifiers

PMID38724872

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.