Evidence map›Paper›PMID 38724857›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Non-intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses: an analysis of clinical characteristics and prognosis.

Jing Zhou, Xinming Zhao, Lifei Feng, Wen Gao, Xiaohong Chen, Jugao Fang, Zhigang Huang, Yang Zhang

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Surgical margin assessment and prognostic impact in sinonasal cancers: a systematic review and meta-analysis.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing ZhouDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Capital Medical University, 1, Dong Jiao Min Xiang Street, Dong Cheng District, Beijing, 100730, China.
Xinming ZhaoDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Capital Medical University, 1, Dong Jiao Min Xiang Street, Dong Cheng District, Beijing, 100730, China.
Lifei FengDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Capital Medical University, 1, Dong Jiao Min Xiang Street, Dong Cheng District, Beijing, 100730, China.
Wen GaoDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Capital Medical University, 1, Dong Jiao Min Xiang Street, Dong Cheng District, Beijing, 100730, China.
Xiaohong ChenDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Capital Medical University, 1, Dong Jiao Min Xiang Street, Dong Cheng District, Beijing, 100730, China.
Jugao FangDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Capital Medical University, 1, Dong Jiao Min Xiang Street, Dong Cheng District, Beijing, 100730, China.
Zhigang HuangDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Capital Medical University, 1, Dong Jiao Min Xiang Street, Dong Cheng District, Beijing, 100730, China.
Yang ZhangDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Capital Medical University, 1, Dong Jiao Min Xiang Street, Dong Cheng District, Beijing, 100730, China. zhangyangent@163.com.ORCID http://orcid.org/0000-0001-9831-7687

Funding

Beijing Municipal Science and Technology Commission, Adminitrative Commission of Zhongguancun Science Park No. Z221100007422045National Natural Science Foundation of China No. 82072997
6 · The paper itself

Abstract

backgroundNon‑intestinal adenocarcinoma of the nasal cavity and paranasal sinuses (non‑ITAC) is a heterogeneous tumour that has rarely been reported in previous studies. We compared and analysed the symptoms, radiographic and pathological features, treatment methods, and prognosis of patients with low-grade (G1) and high-grade (G3) tumours.

methodsThis was a retrospective study included 22 patients with pathologically confirmed non-ITAC of the nasal cavity and paranasal sinuses who were treated between January 2008 and December 2021 at a single centre. Of these, 11 patients had G1 tumours, and 11 patients had G3 tumours. Clinicopathological features, treatment methods, and survival outcomes were analysed.

resultsThe median follow-up period was 48.5 months. Nasal congestion was the most common initial symptom, and the nasal cavity was the most frequently involved site. For G1 tumours, the main treatment was simple surgery, 1 and 3‑year overall survival (OS) rates were 100 and 88.9%, while the 1 and 3‑year local control (LC) rates were 100 and 100%, respectively. For G3 tumours, the main treatments were surgery combined with radiotherapy and/or chemotherapy,1 and 3‑year OS rates were 72.7 and 72.7%, while the 1 and 3‑year LC rates were 100 and 90.91%, respectively. G3 tumours was associated with significantly shorter overall survival than G1 tumours (P = 0.035). Patients with stage III-IV showed shorter overall survival compared to stage I-II patients (P = 0.035).

conclusionsNon-ITAC of the nasal cavity and paranasal sinuses may frequently occur in the nasal cavity. The main treatment modality is surgery, supplemented by radiotherapy and chemotherapy. Pathological grade and tumour stage were poor prognostic factors for the disease.

Indexed as

AdenocarcinomaNasal CavityNose NeoplasmsParanasal Sinus NeoplasmsAdultAgedFemaleHumansMaleMiddle AgedNeoplasm GradingNeoplasm StagingPrognosisRetrospective StudiesSurvival RateMalignant tumours of the nasal cavity and paranasal sinusesNon-intestinal-type adenocarcinomaRetrospective study

Identifiers

PMID38724857

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.