Evidence map›Paper›PMID 38724810›Full record

ArticleBulletin of experimental biology and medicine2024

Alpha Diversity Indices as Indicators of the Variability of Gut Microbiota in Obese Adolescents of Different Ethnicities.

E S Klimenko, N L Belkova, L V Rychkova, M A Darenskaya, O A Tugarinova, N V Semenova, Yu S Savinova, O V Bugun, D B Balzhirova, L I Kolesnikova

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Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

E S KlimenkoScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia. klimenko.elizabet@gmail.com.
N L BelkovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
L V RychkovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
M A DarenskayaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
O A TugarinovaTarbagatai Central Region Clinic, Tarbagatai, Republic of Buryatiya, Russia.
N V SemenovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
Yu S SavinovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
O V BugunScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
D B BalzhirovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
L I KolesnikovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We compared alpha diversity indices of the intestinal microbiota in adolescents with obesity and normal body weight, taking into account their ethnicity. Intestinal biocenosis was studied by metasequencing of amplicon libraries of V3-V4 fragments of the 16S rRNA gene. The alpha diversity of the microbiota was assessed using classical and alternative indices. Statistically significant differences in intestinal microbiota were observed between Russians with obesity and Buryats with normal body weight, as well as between Russians with obesity and Buryats with obesity when assessing the Shannon-Weaver, Chao1 indices, Faith phylogenetic diversity index, ACE, Fisher, Gini coefficient, Margalef, and Menkhinik indices. It was shown that alpha diversity indices can be used to assess significance of differences and variability of the intestinal microbiota in multifactorial diseases such as obesity in adolescents; however, the scope of application of the criteria should be considered.

Indexed as

Gastrointestinal MicrobiomeObesityPhylogenyRNA, Ribosomal, 16SAdolescentEastern European PeopleEthnicityFecesFemaleHumansMaleNorth Asian PeoplePediatric ObesityRussiaRNA, Ribosomal, 16Sadolescentsalpha diversity indicesethnicity aspectgut microbiotaobesity

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.