ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024
Japanese value set for the EORTC QLU-C10D: A multi-attribute utility instrument based on the EORTC QLQ-C30 cancer-specific quality-of-life questionnaire.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed.
- Assessing the health utility values of patients with six common cancers in China using the QLU-C10D: A cross-sectional survey.iScience · 2026Article
- Cancer specific health utilities - QLU-C10D country value sets for Belgium, Hungary, Portugal and the Republic of Korea - an international valuation study.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- What do HTA agencies need for generating health-related quality of life evidence? Findings from a global survey.International journal of technology assessment in health care · 2026Article
- Developing a patient-based utility value set for the EORTC QLU-C10D using the OPUF method in Chinese cancer patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Japanese value set for the Functional Assessment of Cancer Therapy Eight Dimension (FACT-8D) cancer-specific preference-based quality of life instrument.Health and quality of life outcomes · 2025Article
- Validation of the Cancer-Specific Preference-Based Measure EORTC QLU-C10D against the Generic Instruments EQ-5D-5L and SF-6Dv2 in a Prospectively Collected Sample of Patients with Cancer in Austria and France.PharmacoEconomics · 2025Article
- Optimal DCE design for modelling nonlinear time preferences in EQ-5D-5L valuation studies: exploration of data from Denmark and Peru.Health and quality of life outcomes · 2025Article
- Valuation survey for SF-6Dv2 in Japan based on the international protocol.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Norwegian and Swedish value sets for the EORTC QLU-C10D utility instrument.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Chinese utility weights for the EORTC cancer-specific utility instrument QLU-C10D.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
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Abstract
purposeThis study aimed to develop a Japanese value set for the EORTC QLU-C10D, a multi-attribute utility measure derived from the cancer-specific health-related quality-of-life (HRQL) questionnaire, the EORTC QLQ-C30. The QLU-C10D contains ten HRQL dimensions: physical, role, social and emotional functioning, pain, fatigue, sleep, appetite, nausea, and bowel problems.
methodsQuota sampling of a Japanese online panel was used to achieve representativeness of the Japanese general population by sex and age (≥ 18 years). The valuation method was an online discrete choice experiment. Each participant considered 16 choice pairs, randomly assigned from 960 choice pairs. Each pair included two QLU-C10D health states and life expectancy. Data were analyzed using conditional logistic regression, parameterized to fit the quality-adjusted life-year framework. Preference weights were calculated as the ratio of each dimension-level coefficient to the coefficient for life expectancy.
resultsA total of 2809 eligible panel members consented, 2662/2809 (95%) completed at least one choice pair, and 2435/2662 (91%) completed all choice pairs. Within dimensions, preference weights were generally monotonic. Physical functioning, role functioning, and pain were associated with the largest utility weights. Intermediate utility weights were associated with social functioning and nausea; the remaining symptoms and emotional functioning were associated with smaller utility decrements. The value of the worst health state was - 0.221, lower than that seen in most other existing QLU-C10D country-specific value sets.
conclusionsThe Japan-specific QLU-C10D value set is suitable for evaluating the cost and utility of oncology treatments for Japanese health technology assessment and decision-making.
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