Evidence map›Paper›PMID 38724576›Full record

ArticleScientific reports2024

Diagnostic biomarker discovery from brain EEG data using LSTM, reservoir-SNN, and NeuCube methods in a pilot study comparing epilepsy and migraine.

Samaneh Alsadat Saeedinia, Mohammad Reza Jahed-Motlagh, Abbas Tafakhori, Nikola Kirilov Kasabov

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samaneh Alsadat SaeediniaComplex Systems Research Laboratory, Iran University of Science and Technology, Tehran, Iran.
Mohammad Reza Jahed-MotlaghComplex Systems Research Laboratory, Iran University of Science and Technology, Tehran, Iran. Jahedmr@iust.ac.ir.
Abbas TafakhoriDepartment of Neurology, School of Medicine, Iranian Center of Neurological Research, Tehran University of Medical Sciences, Tehran, Iran.
Nikola Kirilov KasabovSchool of Engineering, Computing and Mathematical Sciences, Auckland University of Technology, Auckland, New Zealand. nkasabov@aut.ac.nz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study introduces a new online spike encoding algorithm for spiking neural networks (SNN) and suggests new methods for learning and identifying diagnostic biomarkers using three prominent deep learning neural network models: deep BiLSTM, reservoir SNN, and NeuCube. EEG data from datasets related to epilepsy, migraine, and healthy subjects are employed. Results reveal that BiLSTM hidden neurons capture biological significance, while reservoir SNN activities and NeuCube spiking dynamics identify EEG channels as diagnostic biomarkers. BiLSTM and reservoir SNN achieve 90 and 85% classification accuracy, while NeuCube achieves 97%, all methods pinpointing potential biomarkers like T6, F7, C4, and F8. The research bears implications for refining online EEG classification, analysis, and early brain state diagnosis, enhancing AI models with interpretability and discovery. The proposed techniques hold promise for streamlined brain-computer interfaces and clinical applications, representing a significant advancement in pattern discovery across the three most popular neural network methods for addressing a crucial problem. Further research is planned to study how early can these diagnostic biomarkers predict an onset of brain states.

Indexed as

BiomarkersBrainElectroencephalographyEpilepsyMigraine DisordersNeural Networks, ComputerAdultAlgorithmsDeep LearningFemaleHumansMalePilot ProjectsBiomarkersDeep BiLSTMDeep reservoir SNNEEG classificationEpilepsyMigraineNeuCubePattern recognitionSpike encoding algorithm

Identifiers

PMID38724576
PMCPMC11082192

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.