Evidence map›Paper›PMID 38724513›Full record

ArticleNature communications2024

Hyphal Als proteins act as CR3 ligands to promote immune responses against Candida albicans.

Tingting Zhou, Norma V Solis, Michaela Marshall, Qing Yao, Rachel Garleb, Mengli Yang, Eric Pearlman, Scott G Filler, Haoping Liu

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Biocontrol efficiency of nativeCurrent research in microbial sciences · 2026
    Article
  6. Article
  7. Antifungal Activities of Multi-Halogenated Indoles Against Drug-ResistantInternational journal of molecular sciences · 2025
    Article
  8. Article
  9. Microorganisms · 2025
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tingting ZhouDepartment of Biological Chemistry, University of California, Irvine, CA, USA.ORCID http://orcid.org/0000-0002-0336-0410
Norma V SolisDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Michaela MarshallDepartment of Physiology and Biophysics, University of California, Irvine, CA, USA.ORCID http://orcid.org/0000-0001-9381-780X
Qing YaoDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Rachel GarlebDepartment of Biological Chemistry, University of California, Irvine, CA, USA.
Mengli YangDepartment of Biological Chemistry, University of California, Irvine, CA, USA.
Eric PearlmanDepartment of Physiology and Biophysics, University of California, Irvine, CA, USA.
Scott G FillerDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID http://orcid.org/0000-0001-7278-3700
Haoping LiuDepartment of Biological Chemistry, University of California, Irvine, CA, USA. h4liu@uci.edu.ORCID http://orcid.org/0000-0003-3489-7103

Funding

Pathogenesis of Fungal KeratitisR01EY018612 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI PEARLMAN, ERIC · 2008 to 2022
$6.9M
Signal sensing, hyphal development and pathognesis of Candida albicansR01GM117111 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LIU, HAOPING · 2017 to 2024
$3.8M
NEI NIH HHS R01 EY018612NIGMS NIH HHS R01 GM117111
6 · The paper itself

Abstract

Patients with decreased levels of CD18 (β2 integrins) suffer from life-threatening bacterial and fungal infections. CD11b, the α subunit of integrin CR3 (CD11b/CD18, α

Indexed as

CandidiasisCD18 AntigensFungal ProteinsLectins, C-TypeMacrophagesAnimalsbeta-GlucansCandida albicansCD11b AntigenDendritic CellsInterleukin-1betaMiceSignal TransductionALS3 protein, Candida albicansbeta-GlucansCD11b AntigenCD18 Antigensdectin-2, mouseFungal ProteinsIL1B protein, mouseInterleukin-1betaLectins, C-Type

Identifiers

PMID38724513
PMCPMC11082240

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.