Evidence map›Paper›PMID 38724446›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2024

Time trends in preemptive kidney transplantation in Europe: an ERA registry study.

Anneke Kramer, Rianne Boenink, Cynthia G Mercado Vergara, Samira Bell, Julia Kerschbaum, Olga L Rodríguez Arévalo, Auxiliadora Mazuecos, Aiko P J de Vries, Anna V Reisæter, Esther H S Wong and 16 more

Abstract read
In one paragraph

Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Calcitriol supplementation after kidney transplantation: results of a double-blinded, randomized, placebo-controlled trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Trial
  2. Kidney replacement therapy trajectories of patients with kidney failure: an ERA Registry study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Article
  3. Article
  4. Kidney Transplantation in Western Balkans: A Regional Blueprint for Access, Capacity, and Equity.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
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  10. Insights into effective fatigue reducing interventions in kidney transplant candidates: a scoping review.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Article
  11. Observational
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Anneke KramerERA Registry, Amsterdam UMC location University of Amsterdam, Department of Medical Informatics, Amsterdam, The Netherlands.ORCID 0000-0002-7560-2669
Rianne BoeninkERA Registry, Amsterdam UMC location University of Amsterdam, Department of Medical Informatics, Amsterdam, The Netherlands.
Cynthia G Mercado VergaraAmsterdam UMC location University of Amsterdam, Department of Medical Informatics, Amsterdam, The Netherlands.
Samira BellScottish Renal Registry, Public Health Scotland, Meridian Court, Glasgow, UK.
Julia KerschbaumAustrian Dialysis and Transplant Registry, Department of Internal Medicine IV - Nephrology and Hypertension, Medical University Innsbruck, Innsbruck, Austria.ORCID 0000-0002-6896-2279
Olga L Rodríguez ArévaloRegistry of Renal Patients of the Valencian Community, General Directorate of Public Health and Addictions, Ministry of Universal Health and Public Health, Valencia, Spain.
Auxiliadora MazuecosDepartment of Nephrology, Hospital Universitario Puerta del Mar, Cádiz, Spain.ORCID 0000-0002-5860-2309
Aiko P J de VriesDepartment of Medicine, Division of Nephrology, Leiden Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-9284-3595
Anna V ReisæterDepartment of Transplantation Medicine, Oslo University hospital, Rikshospitalet, Norway.
Esther H S WongUK Kidney Association, UK Renal Registry, University of Bristol, Bristol, UK.
Torbjörn LundgrenDepartment of Transplantation Surgery, Karolinska University Hospital, Stockholm, Sweden.
María O ValentinNephrology Department, Valdecilla Hospital, University of Cantabria, IDIVAL, Santander, Spain.
Flor A Ordoñez AlvarezPediatric Nephrology. Hospital Central de Asturias, Oviedo, Spain.
Edoardo MelilliDepartment of Nephrology, Hospital Universitari de Bellvitge (HUB), Barcelona, Spain.ORCID 0000-0001-6965-3745
Patrik FinneAbdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Mårten SegelmarkDepartment of Clinical Sciences, Lund University and Department of Endocrinology, Nephrology and Rheumatology, Skane University Hospital, Lund, Sweden.ORCID 0000-0002-1221-0772
Cécile CouchoudREIN Registry, Agence de la biomédecine, Saint-Denis La Plaine, France.ORCID 0000-0002-9273-660X
Søren S SørensenDepartment of Nephrology P, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.
Pietro Manuel FerraroFondazione Policlinico Universitario A. Gemelli IRCCS, UOC Nefrologia, Rome, Italy.
Miha ArnolDepartment of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Mustafa AriciDepartment of Nephrology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Alberto OrtizFundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain.ORCID 0000-0002-9805-9523
Kitty J JagerERA Registry, Amsterdam UMC location University of Amsterdam, Department of Medical Informatics, Amsterdam, The Netherlands.ORCID 0000-0003-0444-8569
Daniel AbramowiczDepartment of Nephrology/Hypertension, Antwerp, University Hospital, Edegem, Belgium.
Vianda S StelERA Registry, Amsterdam UMC location University of Amsterdam, Department of Medical Informatics, Amsterdam, The Netherlands.ORCID 0000-0002-0007-1947
Rachel HellemansDepartment of Nephrology/Hypertension, Antwerp, University Hospital, Edegem, Belgium.

Funding

Antwerp University HospitalDepartment of NephrologyEuropean Renal Association
6 · The paper itself

Abstract

backgroundPreemptive kidney transplantation (PEKT) has better outcomes when compared with transplantation after dialysis. We aimed to examine trends in PEKT between 2000 and 2019 in Europe and to provide an overview of associated policies, barriers and initiatives.

methodsAdult patients from 12 European countries who received a preemptive kidney transplant were included. The representatives of the registries providing these data were questioned on the policies, barriers and initiatives around PEKT.

resultsBetween 2000 and 2019, 20 251 adults underwent PEKT [11 169 from living donors (LDs), 8937 from deceased donors (DDs)]. The proportion of first kidney transplantations that were preemptive more than doubled from 7% in 2000 to 18% in 2019, reflecting a similar relative increase for LD kidney recipients (from 21% to 43%) and DD kidney recipients (from 4% to 11%). Large international differences were found. The increase in PEKT was observed across all age, sex and primary renal disease groups. Countries had similar criteria for preemptive waitlisting. Barriers mentioned included donor shortage, late referral to the transplant center and long donoror recipient work-up. Suggested initiatives included raising awareness on the possibility of PEKT, earlier start and shorter work-up time for recipient and LD.

conclusionsOver the last two decades the proportion of patients receiving a first kidney transplant preemptively has more than doubled, reflecting a similar relative increase for living and DD kidney recipients.

Indexed as

Kidney TransplantationRegistriesAdultAgedEuropeFemaleGraft SurvivalHumansKidney Failure, ChronicLiving DonorsMaleMiddle AgedTime FactorsWaiting ListsbarriersEuropepreemptive kidney transplantationtrends

Identifiers

PMID38724446
PMCPMC11648960

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.