Evidence map›Paper›PMID 38724221›Full record

ArticleBMJ open respiratory research2024

Psychometric analysis of the modified COVID-19 Yorkshire Rehabilitation Scale (C19-YRSm) in a prospective multicentre study.

Adam Smith, Darren Greenwood, Mike Horton, Thomas Osborne, Madeline Goodwin, Román Rocha Lawrence, Darren Winch, Paul Williams, Ruairidh Milne, LOCOMOTION consortium and 1 more

Abstract readMulticenter Study
In one paragraph

Article in BMJ open respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Review
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  11. The EQ-5D-5L and Minimal Important Change in Long COVID.Advances in rehabilitation science and practice
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adam SmithLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK a.b.smith@leeds.ac.uk.ORCID http://orcid.org/0000-0002-5750-7772
Darren GreenwoodLeeds Institute for Data Analytics, University of Leeds, Leeds, UK.
Mike HortonAcademic Department of Rehabilitation Medicine, University of Leeds, Leeds, UK.
Thomas OsborneLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.
Madeline GoodwinLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.
Román Rocha LawrenceELAROS 24/7 Digital Company, Sheffield, UK.
Darren WinchKent & Medway ICB Patient Reference Group, Kent, UK.
Paul WilliamsHertfordshire Community NHS Trust, Welwyn Garden City, UK.
Ruairidh MilneUniversity of Southampton, Southampton, UK.
LOCOMOTION consortium
Manoj SivanLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong COVID (LC) is a novel multisystem clinical syndrome affecting millions of individuals worldwide. The modified COVID-19 Yorkshire Rehabilitation Scale (C19-YRSm) is a condition-specific patient-reported outcome measure designed for assessment and monitoring of people with LC.

objectivesTo evaluate the psychometric properties of the C19-YRSm in a prospective sample of people with LC.

methods1314 patients attending 10 UK specialist LC clinics completed C19-YRSm and EuroQol 5D-5L (EQ-5D-5L) longitudinally. Scale characteristics were derived for C19-YRSm subscales (Symptom Severity (SS), Functional Disability (FD) and Overall Health (OH)) and internal consistency (Cronbach's alpha). Convergent validity was assessed using the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue Scale. Known groups validity was assessed for the Other Symptoms subscale as tertiles, as well as by hospitalisation and intensive care admission. Responsiveness and test-retest reliability was evaluated for C19-YRSm subscales and EQ-5D-5L. The minimal important difference (MID) and minimal clinically important difference (MCID) were estimated. Confirmatory factor analysis was applied to determine the instrument's two-factor structure.

resultsC19-YRSm demonstrated good scale characteristic properties. Item-total correlations were between 0.37 and 0.65 (for SS and FD), with good internal reliability (Cronbach's alphas>0.8). Item correlations between subscales ranged between 0.46 and 0.72. Convergent validity with FACIT was good (-0.46 to -0.62). The three subscales discriminated between different levels of symptom burden (p<0.001) and between patients admitted to hospital and intensive care. There was moderate responsiveness for the three subscales ranging from 0.22 (OH) to 0.50 (SS) which was greater than for the EQ-5D-5L. Test-retest reliability was good for both SS 0.86 and FD 0.78. MID was 2 for SS, 2 for FD and 1 for OH; MCID was 4 for both the SS and FD. The factor analysis supported the two-factor SS and FD structure.

conclusionsThe C19-YRSm is a condition-specific, reliable, valid and responsive patient-reported outcome measure for LC.

Indexed as

COVID-19Patient Reported Outcome MeasuresPsychometricsSARS-CoV-2AdultAgedFemaleHumansMaleMiddle AgedPost-Acute COVID-19 SyndromeProspective StudiesQuality of LifeReproducibility of ResultsSeverity of Illness IndexUnited KingdomCOVID-19Patient Outcome Assessment

Identifiers

PMID38724221
PMCPMC11086182

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.