Evidence map›Paper›PMID 38724203›Full record

ArticleAJNR. American journal of neuroradiology2024

T2-FLAIR Mismatch: An Imaging Biomarker for Children's

E A van Maren, J W Dankbaar, P Wesseling, S Plasschaert, A Muhlebner, E W Hoving, P A Robe, T J Snijders, R Hoogendijk, M E G Kranendonk and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Angiocentric glioma: a single center experience and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

E A van MarenFrom the Department of Radiology and Nuclear Medicine (E.A.v.M., J.W.D., M.H.L.), University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0009-0004-7943-3497
J W DankbaarFrom the Department of Radiology and Nuclear Medicine (E.A.v.M., J.W.D., M.H.L.), University Medical Center Utrecht, Utrecht, the Netherlands j.w.dankbaar@umcutrecht.nl.ORCID 0000-0003-4646-9587
P WesselingPrincess Máxima Center for Pediatric Oncology (P.W., S.P., E.W.H., R.H., M.E.G.K., M.H.L.), Utrecht, the Netherlands.
S PlasschaertPrincess Máxima Center for Pediatric Oncology (P.W., S.P., E.W.H., R.H., M.E.G.K., M.H.L.), Utrecht, the Netherlands.ORCID 0000-0003-3391-3618
A MuhlebnerDepartment of Pathology (A.M.), University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0000-0001-9102-7353
E W HovingPrincess Máxima Center for Pediatric Oncology (P.W., S.P., E.W.H., R.H., M.E.G.K., M.H.L.), Utrecht, the Netherlands.
P A RobeDepartment of Neurosurgery (E.W.H., P.A.R.), University Medical Center Utrecht, Utrecht, the Netherlands.
T J SnijdersDepartment of Neurology (T.J.S.), UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0000-0003-0857-081X
R HoogendijkPrincess Máxima Center for Pediatric Oncology (P.W., S.P., E.W.H., R.H., M.E.G.K., M.H.L.), Utrecht, the Netherlands.ORCID 0000-0002-8033-2093
M E G KranendonkPrincess Máxima Center for Pediatric Oncology (P.W., S.P., E.W.H., R.H., M.E.G.K., M.H.L.), Utrecht, the Netherlands.
M H LequinFrom the Department of Radiology and Nuclear Medicine (E.A.v.M., J.W.D., M.H.L.), University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0000-0001-7488-1734

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeT2-FLAIR mismatch is a highly specific imaging biomarker of MATERIALS AND

methodsWe evaluated MR imaging examinations of all pediatric patients, performed at the Princess Máxima Center for Pediatric Oncology and the University Medical Center Utrecht between January 2012 and January 2023, with the histomolecular diagnosis of

resultsNineteen pediatric patients were diagnosed with either

conclusionsIn our pediatric population, T2-FLAIR mismatch was more often found in

Indexed as

AstrocytomaBrain NeoplasmsGliomaMagnetic Resonance ImagingProto-Oncogene Proteins c-mybAdolescentBiomarkers, TumorChildChild, PreschoolFemaleHumansInfantIsocitrate DehydrogenaseMaleMutationProto-Oncogene ProteinsBiomarkers, TumorIsocitrate DehydrogenaseMYBL1 protein, humanMYB protein, humanProto-Oncogene ProteinsProto-Oncogene Proteins c-mybTrans-Activators

Identifiers

PMID38724203
PMCPMC11288608

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.