Evidence map›Paper›PMID 38723193›Full record

ArticleEnvironmental technology2025

Analysis of microcystins in alum water treatment sludges: holding times, temperatures, linearity of response, and sensitivity to pre-coagulation cell titers.

Peyton Woodruff, Morgan McNeely, Toby Sanan, Nicholas Dugan

Abstract read
In one paragraph

Article in Environmental technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Early Detection Methods for Toxic Cyanobacteria Blooms.Pathogens (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peyton WoodruffU.S. Environmental Protection Agency, Cincinnati, OH, USA.
Morgan McNeelyU.S. Environmental Protection Agency, Cincinnati, OH, USA.
Toby SananU.S. Environmental Protection Agency, Cincinnati, OH, USA.
Nicholas DuganU.S. Environmental Protection Agency, Cincinnati, OH, USA.ORCID 0000-0003-4513-5198

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

ELISA assays are a potential tool to screen for dissolved or cell bound microcystins in drinking water treatment sludges. In order to evaluate this potential more thoroughly, experiments were performed in alum sludges to: (1) evaluate the impacts of sample storage times, temperatures, and sludge composition on spiked microcystin-LR recovery by ELISA; (2) examine the linearity of ELISA responses to spiked microcystin-LR as a function of sludge composition; and (3) examine the sensitivity ELISA and LC/MS/MS to five different concentrations of microcystin-producing cyanobacteria entrained in sludges of two different compositions. During storage experiments, microcystin recovery efficiencies ranged from 85% to 125% across the range of 12 storage time and temperature combinations with recovery efficiencies in 7 of the 12 combinations falling into the 90% to 110% range. During the linearity experiments, linear models fit ELISA responses in all sludge compositions with R

Indexed as

Alum CompoundsEnzyme-Linked Immunosorbent AssayMicrocystinsSewageWater PurificationChromatography, LiquidCyanobacteriaTandem Mass SpectrometryTemperatureAlum Compoundsaluminum sulfateMicrocystinsSewagecyanobacteriaELISALC/MS/MSmicrocystinsludge

Identifiers

PMID38723193
PMCPMC11786967

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.