Evidence map›Paper›PMID 38722459›Full record

ArticleDrug delivery and translational research2025

Quercetin loaded polymeric dissolving microarray patches: fabrication, characterisation and evaluation.

Qonita Kurnia Anjani, Natalia Moreno-Castellanos, Masoud Adhami, Delly Ramadon, Jangga Jangga, Ryan F Donnelly

Abstract read
In one paragraph

Article in Drug delivery and translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. SoluplusInternational journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qonita Kurnia AnjaniSchool of Pharmacy, Medical Biology Centre, Queen's University Belfast, 97 Lisburn Road, Belfast, Northern Ireland, BT9 7BL, UK.
Natalia Moreno-CastellanosBasic Science Department, Faculty of Health, Universidad Industrial de Santander, Bucaramanga, 680001, Colombia.
Masoud AdhamiSchool of Pharmacy, Medical Biology Centre, Queen's University Belfast, 97 Lisburn Road, Belfast, Northern Ireland, BT9 7BL, UK.
Delly RamadonFaculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia.
Jangga JanggaFakultas Farmasi, Universitas Megarezky, Jl. Antang Raya No. 43, Makassar, 90234, Indonesia.
Ryan F DonnellySchool of Pharmacy, Medical Biology Centre, Queen's University Belfast, 97 Lisburn Road, Belfast, Northern Ireland, BT9 7BL, UK. r.donnelly@qub.ac.uk.ORCID 0000-0002-0766-4147

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quercetin, a natural compound, shows promising potential in wound healing by reducing fibrosis, limiting scar formation, and boosting fibroblast proliferation. However, its effectiveness is hindered by poor solubility, resulting in low bioavailability and necessitating high doses for therapeutic efficacy. This study presents a novel approach, fabricating quercetin-loaded microarray patches (MAPs) using widely employed solubility enhancement strategies. Fabricated MAPs exhibited favourable mechanical strength and could be inserted into excised porcine skin to a depth of 650 μm. Furthermore, formulations containing Soluplus

Indexed as

QuercetinSkinSolubilityAdministration, CutaneousAnimalsAnti-Inflammatory AgentsDrug LiberationHumansKeratinocytesPolyethylene GlycolsPolyvinylsSkin AbsorptionSwineTransdermal PatchWound HealingAnti-Inflammatory AgentsPolyethylene Glycolspolyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymerPolyvinylsQuercetinCell proliferationDissolving microarray patchesInflammation activityQuercetin

Identifiers

PMID38722459
PMCPMC11614984

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.