Evidence map›Paper›PMID 38722446›Full record

ArticleEJNMMI physics2024

The significance of partial volume effect on the estimation of hypoxic tumour volume with [

Athanasios Kafkaletos, Michael Mix, Ilias Sachpazidis, Montserrat Carles, Alexander Rühle, Juri Ruf, Anca L Grosu, Nils H Nicolay, Dimos Baltas

Abstract read
In one paragraph

Article in EJNMMI physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Surrogating tumour cell density in head and neck cancer: [Radiation oncology (London, England) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Athanasios KafkaletosDivision of Medical Physics, Department of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, German Cancer Consortium (DKTK), partner site DKTK-Freiburg, University of Freiburg, Freiburg, Germany. athanasios.kafkaletos@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0002-9309-7803
Michael MixDepartment of Nuclear Medicine, Medical Centre - University of Freiburg, Faculty of Medicine, German Cancer Consortium (DKTK), partner site DKTK-Freiburg, University of Freiburg, Freiburg, Germany.
Ilias SachpazidisDivision of Medical Physics, Department of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, German Cancer Consortium (DKTK), partner site DKTK-Freiburg, University of Freiburg, Freiburg, Germany.
Montserrat CarlesBiomedical Imaging Research Group (GIBI230-PREBI) and Imaging La Fe Node at Distributed Network for Biomedical Imaging (ReDIB) Unique Scientific and Technical Infrastructures (ICTS), La Fe Health Research Institute, Valencia, Spain.
Alexander RühleDepartment of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, German Cancer Consortium (DKTK), partner site DKTK-Freiburg, University of Freiburg, Freiburg, Germany.
Juri RufDepartment of Nuclear Medicine, Medical Centre - University of Freiburg, Faculty of Medicine, German Cancer Consortium (DKTK), partner site DKTK-Freiburg, University of Freiburg, Freiburg, Germany.
Anca L GrosuDepartment of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, German Cancer Consortium (DKTK), partner site DKTK-Freiburg, University of Freiburg, Freiburg, Germany.
Nils H NicolayDepartment of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, German Cancer Consortium (DKTK), partner site DKTK-Freiburg, University of Freiburg, Freiburg, Germany.
Dimos BaltasDivision of Medical Physics, Department of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, German Cancer Consortium (DKTK), partner site DKTK-Freiburg, University of Freiburg, Freiburg, Germany.

Funding

Deutschen Konsortium für Translationale Krebsforschung FR01-SOB-BioImag-Nic (DKTK Freiburg)
6 · The paper itself

Abstract

backgroundThe purpose of this study was to evaluate how a retrospective correction of the partial volume effect (PVE) in [

resultsThe application of the proposed correction method resulted in a statistically significant increase of both the hypoxic subvolume (171% at W0, 691% at W2 and 4.60 × 10

conclusionsThe proposed PVE-correction method resulted in a statistically significant increase of the hypoxic fraction (HF) with p < 0.001 and demonstrated results in better agreement with published HF data for HNSCC. To summarise, the proposed RC-based correction method can be a useful tool for a retrospective compensation against PVE.

Indexed as

FMISOHNSCCHypoxiaPartial volume effectsPET

Identifiers

PMID38722446
PMCPMC11082115

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.