Evidence map›Paper›PMID 38721980›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2025

Associations Between Antiretroviral Regimen and Changes in Blood Pressure: Results From the D2EFT Study.

Phyo Pyae Nyein, Kathy Petoumenos, Margaret Borok, Nnakelu Eriobu, Nagalingeswaran Kumarasamy, Anchalee Avihingsanon, Iskandar Azwa, Sounkalo Dao, Mohamed Cisse, Nila J Dharan and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Reply to Dr Martinez: Refining Our Understanding of the Association Between Integrase Inhibitor Therapy and Elevations in Blood Pressure.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  6. Review
  7. Observational
  8. Incident Hypertension with Antiretroviral Therapy in the OPERA Cohort.Journal of the International Association of Providers of AIDS Care
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Phyo Pyae NyeinThe Kirby Institute, University of New South Wales, Sydney, Australia.
Kathy PetoumenosThe Kirby Institute, University of New South Wales, Sydney, Australia.
Margaret BorokUniversity of Zimbabwe Clinical Research Centre, Harare, Zimbabwe.
Nnakelu EriobuInternational Research Center of Excellence (IREC), Institute of Human Virology Nigeria, Abuja, Nigeria.
Nagalingeswaran KumarasamyVHS Infectious Diseases Medical Centre, Chennai Antiviral Research and Treatment Clinical Research Site (CART CRS) Voluntary Health Services (VHS), Chennai, India.
Anchalee AvihingsanonThe HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Iskandar AzwaUniversity of Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia.
Sounkalo DaoUniversity Clinical Research Centre (UCRC), Bamako, Mali.
Mohamed CisseCentre de Traitement Ambulatoire de Donka (Hospital de Jour), Université Gamal Abdel Nasser de Conakry, Conakry, Guinea.
Nila J DharanThe Kirby Institute, University of New South Wales, Sydney, Australia.
Josh HansonThe Kirby Institute, University of New South Wales, Sydney, Australia.
Gail V MatthewsThe Kirby Institute, University of New South Wales, Sydney, Australia.

Funding

National Health and Medical Research Council, Australia APP1104610National Institute of Allergy and Infectious DiseasesNIAID NIH HHS 18Q065NIAID NIH HHS 19Q120NIH HHSUNITAIDViiV Healthcare, and Janssen
6 · The paper itself

Abstract

In this randomized controlled study, individuals taking dolutegravir+darunavir/ritonavir had greater increases in systolic and diastolic blood pressure than those taking 2 nucleoside reverse-transcriptase inhibitors+darunavir/ritonavir at week-48. The difference remained significant after controlling for confounding factors, including weight gain.

Indexed as

Anti-HIV AgentsAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveBlood PressureHIV InfectionsAdultClinical Trials, Phase IV as TopicDolutegravirFemaleHeterocyclic Compounds, 3-RingHumansMaleMiddle AgedMulticenter Studies as TopicOxazinesPiperazinesAnti-HIV AgentsAnti-Retroviral AgentsDolutegravirHeterocyclic Compounds, 3-RingOxazinesPiperazinesPyridonesRitonavircardiovascular riskdolutegravirHIVhypertensionlow- and middle-income countries

Identifiers

PMID38721980
PMCPMC11797029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.