ArticleFrontiers in microbiology2024
Unraveling the dynamic transcriptomic changes during the dimorphic transition of
Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Coordinated gene family evolution shapes the genome of dimorphic Mucorales.Nature communications · 2026Article
- ClinicalFrontiers in fungal biology · 2026Article
- Functional diversification of the MADS-box gene family in fine-tuning the dimorphic transition ofmSystems · 2025Article
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Authors and funding
7 authors.
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Abstract
Introduction: Systemic dimorphic fungi pose a significant public health challenge, causing over one million new infections annually. The dimorphic transition between saprophytic mycelia and pathogenic yeasts is strongly associated with the pathogenesis of dimorphic fungi. However, despite the dynamic nature of dimorphic transition, the current omics studies focused on dimorphic transition primarily employ static strategies, partly due to the lack of suitable dynamic analytical methods. Methods: We conducted time-course transcriptional profiling during the dimorphic transition of Results: By using DyGAM-NS, model, we identified 5,223 DTIGs of Discussion: Our study elucidates the dynamic transcriptional profile changes during the dimorphic transition of
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