Evidence map›Paper›PMID 38721403›Full record

ArticleJournal of immunotherapy and precision oncology2024

Impact of COVID-19 on Management and Outcomes of Oncology Patients: Results of MENA COVID-19 and Cancer Registry (MCCR).

Abdul-Rahman Jazieh, Adda Bounedjar, Hikmat Abdel-Razeq, Elif Berna Koksoy, Jawaher Ansari, Arafat H Tfayli, Emad M Tashkandi, Wasil A Jastaniah, Mohamed Osama Alorabi, Amira D Darwish and 10 more

Abstract read
In one paragraph

Article in Journal of immunotherapy and precision oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Abdul-Rahman JaziehCincinnati Cancer Advisors, Cincinnati, OH, USA.ORCID https://orcid.org/0000-0001-5465-7698
Adda BounedjarUniversité Blida 1 Laboratoire de Cancérologie, Faculté de Médecine, Blida, Algeria.
Hikmat Abdel-RazeqKing Hussein Cancer Center, Amman, Jordan.
Elif Berna KoksoyAnkara University Faculty of Medicine, Medical Oncology Department, Ankara, Turkey.
Jawaher AnsariTawam Hospital, Al Ain, United Arab Emirates.
Arafat H TfayliAmerican University of Beirut, Beirut, Lebanon.
Emad M TashkandiCollege of Medicine, Umm AlQura University and Oncology Center, King Abdullah Medical City, Makkah, Saudi Arabia.
Wasil A JastaniahKing Faisal Specialist Hospital & Research Center - Jeddah, Jeddah, Saudi Arabia.
Mohamed Osama AlorabiShefaa Al Orman Hospital and Clinical Oncology Department, Faculty of Medicine - Ain Shams University, Cairo, Egypt.
Amira D DarwishNCI Cairo University and Baheya Foundation for Early Detection and Treatment of Breast Cancer, Cairo, Egypt.
Ahmed Magdy RabeaShefaa Al Orman Hospital and National Cancer Institute Cairo, Cairo, Egypt.
Ashwaq Al OlayanDepartment of Oncology, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia.
Fahad IbnshamsahKing Fahad Specialist Hospital, Dammam, Saudi Arabia.
Hassan ErrihaniNational Institute of Oncology, Mohammed V University, Rabat, Morocco.
Mohammad Omar AlKaiyatOncology Department, King Abdulaziz Medical City, Ministry of National Guard, Riyadh, Saudi Arabia.
Fazal HussainUniversity of Texas Health Science Center, San Antonio, TX, USA.
Khaled AlkattanCollege of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Suanna Steeby BruinoogeAmerican Society of Clinical Oncology, Alexandria, VA, USA.
Elizabeth Garrett-MayerAmerican Society of Clinical Oncology, Alexandria, VA, USA.
Hani TamimAmerican University of Beirut, Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Despite extensive studies of the impact of COVID-19 on patients with cancer, there is a dearth of information from the Middle East and North Africa (MENA) region. Our study aimed to report pertinent MENA COVID-19 and Cancer Registry (MCCR) findings on patient management and outcomes. Methods: MCCR was adapted from the American Society of Clinical Oncology COVID-19 Registry to collect data specifically from patients with cancer and SARS-CoV-2 infection from 12 centers in eight countries including Saudi Arabia, Jordan, Lebanon, Turkey, Egypt, Algeria, United Arab Emirates, and Morocco. The Registry included data on patients and disease characteristics, treatment, and patient outcomes. Logistic regression was used to assess associations with mortality. Results: Between November 29, 2020, and June 8, 2021, data were captured on 2008 patients diagnosed with COVID-19 from the beginning of the pandemic. Median age was 56 years (16-98), 56.4% were females, and 26% were current or ex-smokers. Breast cancer (28.5%) was the leading diagnosis and 50.5% had metastatic disease. Delays of planned treatment (>14 days) occurred in 80.3% for surgery, 48.8% for radiation therapy, and 32.9% for systemic therapy. Significant reduction in the delays of all three treatment modalities occurred after June 1, 2020. All-cause mortality rates at 30 and 90 days were 17.1% and 23.4%, respectively. All-cause mortality rates at 30 days did not change significantly after June 1, 2020; however, 90-day mortality increased from 33.4% to 42.9% before and after that date ( Conclusion: Patients with cancer in the MENA region experienced similar risks and outcome of COVID-19 as reported in other populations. Although there were fewer treatment delays after June 1, 2020, 90-day mortality increased, which may be attributed to other risk factors such as disease progression or new patients who presented with more advanced disease.

Indexed as

cancercancer careCOVID-19MENA Regionmortality

Identifiers

PMID38721403
PMCPMC11075473

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.