Evidence map›Paper›PMID 38721280›Full record

ArticleWellcome open research2022

Impact of the COVID-19 pandemic on routine surveillance for adults with chronic hepatitis B virus (HBV) infection in the UK.

Cori Campbell, Tingyan Wang, David A Smith, Oliver Freeman, Theresa Noble, Kinga A Várnai, Steve Harris, Hizni Salih, Gail Roadknight, Stephanie Little and 24 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Wellcome open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05690607 (Small Volume Blood Testing Validity and Acceptability for HIV-1 and Hepatitis B), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05690607 unknown statusnot on this mapstarted 2023, after this paper: background citation

Small Volume Blood Testing Validity and Acceptability for HIV-1 and Hepatitis B

TypeobservationalSponsorCentral and North West London NHS Foundation TrustRan2023 to 2024Enrolled300ConditionsHIV Infections, Hepatitis BArmsDoctors Laboratory TINIES small volume blood testing kit
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Cori CampbellNuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0001-5890-7105
Tingyan WangNuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-8351-9494
David A SmithNIHR Health Informatics Collaborative, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.ORCID https://orcid.org/0000-0001-7778-7137
Oliver FreemanNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.
Theresa NobleNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.
Kinga A VárnaiNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0001-5695-9497
Steve HarrisNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-0899-325X
Hizni SalihNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-5283-7799
Gail RoadknightNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-1158-0181
Stephanie LittleNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.
Ben GlampsonNIHR Health Informatics Collaborative, Imperial College Healthcare NHS Trust, London, UK.
Luca MercuriNIHR Health Informatics Collaborative, Imperial College Healthcare NHS Trust, London, UK.ORCID https://orcid.org/0000-0001-9076-5717
Dimitri PapadimitriouNIHR Health Informatics Collaborative, Imperial College Healthcare NHS Trust, London, UK.
Christopher R JonesDepartment of Infectious Disease, Imperial College London, London, UK.
Vince TaylorCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Afzal ChaudhryCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Hang PhanNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Florina BorcaNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Josune OlzaNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.ORCID https://orcid.org/0000-0001-8840-8542
Frazer WarrickerUniversity Hospital Southampton NHS Foundation Trust, Southampton, UK.
Luis RomãoUniversity College London Hospitals NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0001-5545-5289
David RamlakhanUniversity College London Hospitals NHS Foundation Trust, London, UK.
Louise EnglishUniversity College London Hospitals NHS Foundation Trust, London, UK.
Paul KlenermanNuffield Department of Medicine, University of Oxford, Oxford, UK.
Monique I AnderssonDepartment of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.ORCID https://orcid.org/0000-0003-0619-1074
Jane CollierDepartment of Hepatology, John Radcliffe Hospital, Oxford, UK.
Eleni NastouliDepartment of Clinical Virology, University College London Hospitals NHS Trust, London, UK.
Salim I KhakooSchool of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
William GelsonCambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Graham S CookeNIHR Health Informatics Collaborative, Imperial College Healthcare NHS Trust, London, UK.ORCID https://orcid.org/0000-0001-6475-5056
Kerrie WoodsNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.
Jim DaviesNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.
Eleanor BarnesNuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-0860-0831
Philippa C MatthewsNuffield Department of Medicine, University of Oxford, Oxford, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Background: To determine the impact of the COVID-19 pandemic on the population with chronic Hepatitis B virus (HBV) infection under hospital follow-up in the UK, we quantified the coverage and frequency of measurements of biomarkers used for routine surveillance (alanine transferase [ALT] and HBV viral load). Methods: We used anonymized electronic health record data from the National Institute for Health Research (NIHR) Health Informatics Collaborative (HIC) pipeline representing five UK National Health Service (NHS) Trusts. Results: We report significant reductions in surveillance of both biomarkers during the pandemic compared to pre-COVID-19 years, both in terms of the proportion of patients who had ≥1 measurement annually, and the mean number of measurements per patient. Conclusions: These results demonstrate the real-time utility of HIC data in monitoring health-care provision, and support interventions to provide catch-up services to minimise the impact of the pandemic. Further investigation is required to determine whether these disruptions will be associated with increased rates of adverse chronic HBV outcomes.

Indexed as

COVID-19epidemiologyHBVhepatitis B virusviral hepatitisvirology

Identifiers

PMID38721280
PMCPMC11077619

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.