Evidence map›Paper›PMID 38721267›Full record

ArticleAPL bioengineering2024

Air-liquid intestinal cell culture allows

Pamela C Cai, Margaret Braunreuther, Audrey Shih, Andrew J Spakowitz, Gerald G Fuller, Sarah C Heilshorn

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in APL bioengineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. High-throughput Mucus Microrheology for Phenotyping and Disease Modeling.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pamela C CaiDepartment of Chemical Engineering, Stanford University, Stanford, California 94305, USA.ORCID https://orcid.org/0000-0002-0838-0402
Margaret BraunreutherDepartment of Chemical Engineering, Stanford University, Stanford, California 94305, USA.ORCID https://orcid.org/0000-0003-0863-8562
Audrey ShihDepartment of Chemical Engineering, Stanford University, Stanford, California 94305, USA.ORCID https://orcid.org/0000-0002-8489-2178
Andrew J SpakowitzORCID https://orcid.org/0000-0002-0585-1942
Gerald G FullerDepartment of Chemical Engineering, Stanford University, Stanford, California 94305, USA.ORCID https://orcid.org/0000-0002-2924-053X
Sarah C HeilshornDepartment of Materials Science and Engineering, Stanford University, Stanford, California 94305, USA.ORCID https://orcid.org/0000-0002-9801-6304

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal health heavily depends on establishing a mucus layer within the gut with physical properties that strike a balance between being sufficiently elastic to keep out harmful pathogens yet viscous enough to flow and turnover the contents being digested. Studies investigating dysfunction of the mucus layer in the intestines are largely confined to animal models, which require invasive procedures to collect the mucus fluid. In this work, we develop a nondestructive method to study intestinal mucus. We use an air-liquid interface culture of primary human intestinal epithelial cells that exposes their apical surface to allow

Identifiers

PMID38721267
PMCPMC11078553

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.