Evidence map›Paper›PMID 38721158›Full record

ArticleCureus2024

Livedoid Vasculopathy with Severe Debilitating Neuropathy in a Prior Professional Athlete.

Ian Del Valle, Devlin J Farr, Shannon Downie, Devin Broadwater, Peter W Barnes, Nam Nguyen, Jamison Hofer

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ian Del ValleInternal Medicine, Keesler Medical Center, Biloxi, USA.
Devlin J FarrInternal Medicine, Keesler Medical Center, Biloxi, USA.
Shannon DownieInternal Medicine, Ohio University Heritage College of Osteopathic Medicine, Dublin, USA.
Devin BroadwaterPathology, Keesler Medical Center, Biloxi, USA.
Peter W BarnesDermatology, Keesler Medical Center, Biloxi, USA.
Nam NguyenRheumatology, Keesler Medical Center, Biloxi, USA.
Jamison HoferNeurology, Keesler Medical Center, Biloxi, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Livedoid vasculopathy (LV) can be a challenging diagnosis with an interesting pathophysiology. LV is an uncommon diagnosis that can be easily mistaken for more common skin conditions, especially in a person of color who may be underrepresented in pathology images used in medical education. LV has an average of five years from initial presentation to diagnosis, possibly due to providers not having it on their differential for lower extremity ulcerations. Prolonged time to diagnosis can potentially lead to life-changing complications. We present a case of a former professional sprinter who became debilitated by neuropathy secondary to complications from LV. He was seen multiple times and had an extensive work-up exploring a broad differential including autoimmune etiologies, hypercoagulable disorders, neuropathies, and other vascular disorders before reaching the diagnosis. This case emphasizes the importance of early diagnosis and treatment with a multidisciplinary team to help prevent the progression of these symptoms. We break down an extensive work-up that involves a multidisciplinary team including dermatology, hematology, neurology, rheumatology, and vascular surgery. This case will also highlight examples of LV in a patient with a dark skin complexion, which can be challenging to find in current literature. We additionally show images that demonstrate many of the classic pathologic findings associated with LV and how those can help lead to the diagnosis along with detailed descriptions of those findings. Classic physical exam findings including atrophic blanche and lower extremity ulcerations are highlighted. We also review LV's history, diagnosis, and treatment to help readers achieve a better understanding of the disease.

Indexed as

atrophie blanchecoagulopathyderm-rheumimmuno-fluorescencelivedoid vasculopathylower extremity ulcersmilitary medicineneuropathypathology dermpunch biopsy

Identifiers

PMID38721158
PMCPMC11077617

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.