Evidence map›Paper›PMID 38721103›Full record

ArticleSouth Asian journal of cancer2024

COVID-19 and Cancer: A Comparison of the Two Important Pandemic Waves in an Indian Cancer Patients' Cohort.

Ullas Batra, Shrinidhi Nathany, Mansi Sharma, Sekhar Saha, Dushyant Kumar, Joslia T Jose, Harkirat Singh

Abstract read
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Article in South Asian journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ullas BatraDepartment of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.ORCID 0000-0003-3306-9824
Shrinidhi NathanySection of Molecular Diagnostics, Department of Pathology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
Mansi SharmaDepartment of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
Sekhar SahaDepartment of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
Dushyant KumarSection of Molecular Diagnostics, Department of Pathology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
Joslia T JoseDepartment of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
Harkirat SinghDepartment of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ullas BatraIt is well known that patients with cancer are at an increased risk of severe COVID-19. There are no reports that depict the differences in outcomes in cancer patients between the two waves of the pandemic. This is a real-world experience aimed at characterizing the differences in demographics, clinical features, treatment details, and outcomes in COVID-19-positive cancer patients between the two pandemic waves. This was a prospective study of all COVID-19-positive cancer patients attending our specialty out-patient department at Rajiv Gandhi Cancer Institute and Research Centre between March 2020 and November 2020 (1st wave) and April 2021 and June 2021 (second wave). All patients diagnosed to have COVID-19 by real-time polymerase chain reaction (RT-PCR) with a biopsy-proven solid organ malignancy attending the medical oncology out-patient department were included during both the waves. A total of 300 patients with proven SARS-CoV-2 infection by either RT-PCR or cartridge based nucleic acid amplification test were encountered, of which 123 were encountered during the first wave of the pandemic and 177 during the second wave. The case fatality rate of the first wave was 9.8%, with a 15-day case fatality rate of 5.6%, whereas for the second wave, it was 13% and 7.2%, respectively. Twelve patients succumbed to COVID-19 disease in the first wave and 23 succumbed in the second. There were no statistically significant correlations; however, the death in the second wave tended to occur more in younger male patients, with comorbidities and history of smoking. There was no relation with ongoing cancer-directed treatment or chemotherapy. Our study is unique in comparing characteristics of the two most important COVID-19 waves and treatment patterns in cancer patients from a single center. The second wave showed a higher CFR, hospital admission rate, and higher frequency of respiratory complications; however, there was no relation to cancer-directed therapy and COVID-19, thus reiterating the fact that cancer treatment should not be halted in the event of a COVID-19 infection.

Indexed as

1st two wavescancercomparisonCOVIDIndia

Identifiers

PMID38721103
PMCPMC11076088

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