Evidence map›Paper›PMID 38720830›Full record

ArticleQuantitative imaging in medicine and surgery2024

Higher perfusion of rectum carcinoma relative to tumor-free rectal wall: quantification by a new imaging biomarker diffusion-derived vessel density (DDVD).

Bao-Lan Lu, Dian-Qi Yao, Yì Xiáng J Wáng, Zhi-Wen Zhang, Zi-Qiang Wen, Ben-Heng Xiao, Shen-Ping Yu

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  9. MRI signal simulation of liverQuantitative imaging in medicine and surgery · 2025
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  10. Influences of the second motion probing gradientQuantitative imaging in medicine and surgery · 2025
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bao-Lan Lu *Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Dian-Qi Yao *Department of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Yì Xiáng J WángDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Zhi-Wen ZhangDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Zi-Qiang WenDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Ben-Heng XiaoDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Shen-Ping YuDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diffusion-derived vessel density (DDVD) is a physiological surrogate of the area of micro-vessels per unit tissue area. DDVD is calculated according to: DDVD(b0b5) = Sb0/ROIarea0 - Sb5/ROIarea5, where Sb0 and Sb5 refer to the tissue signal when Methods: MRI was performed with a 3.0-T magnet. Diffusion weighted image with Results: The median value of the DDVDr(b0b5) for non-mucinous RCs was 1.430, with the majority of RCs showing a higher DDVD than the adjacent tumor-free wall [i.e., with DDVDr(b0b5) >1]. 90.3% (102/113) of non-mucinous RCs were hypervascular, 1.77% (2/113) were iso-vascular, and 7.96% (9/113) were hypovascular. The median value of the DDVDr(b0b5) for mucinous RCs was 1.660. 73.3% (11/15) of mucinous RCs were hypervascular, and 26.7% (4/15) were hypovascular. A trend (P=0.09) was noted that earlier clinical grades non-mucinous RCs had a higher DDVDr(b0b5) than those of the advanced clinical grades (2.245 for grade 0&I, 1.460 for grade II, 1.430 for grade III, 1.130 for grade IV). A non-significant trend was noted with well and moderately differentiated non-mucinous RCs had a higher DDVDr(b0b5)than that of poorly differentiated non-mucinous RCs (median: 1.460 Conclusions: DDVD results in this study approximately agree with contrast agent dynamically enhanced CT literature data.

Indexed as

diffusion-weighted imaging (DWI)perfusionRectal carcinomas (RCs)

Identifiers

PMID38720830
PMCPMC11074728

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.