ArticleFEBS open bio2024
HELQ deficiency impairs the induction of primordial germ cell-like cells.
Cong Wan, Yaping Huang, Xingguo Xue, Gang Chang, Mei Wang, Xiao-Yang Zhao, Fang Luo, Zhi-Zhong Tang
Erratum issuedAbstract read
In one paragraphArticle in FEBS open bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
8 authors.
Cong WanMaoming People's Hospital, China.
Yaping HuangState Key Laboratory of Organ Failure Research, Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Xingguo XueState Key Laboratory of Organ Failure Research, Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Gang ChangDepartment of Biochemistry and Molecular Biology, Shenzhen University Health Science Center, China.
Mei WangState Key Laboratory of Organ Failure Research, Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Xiao-Yang ZhaoState Key Laboratory of Organ Failure Research, Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.ORCID 0000-0003-2544-8293 Fang LuoState Key Laboratory of Organ Failure Research, Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhi-Zhong TangMaoming People's Hospital, China.
Funding
High-level Hospital Construction Research Project of Maoming People's HospitalNational Key R&D Program of China 2020YFA0113300National Key R&D Program of China 2022YFA0806303National Key R&D Program of China 2022YFC2702603National Natural Science Foundation of China 31970787National Natural Science Foundation of China 32170869National Natural Science Foundation of China 32200670National Natural Science Foundation of China 32370911Natural Science Foundation of Shenzhen Municipality JCYJ20210324120212033Natural Science Foundation of Shenzhen Municipality JCYJ20230808105421043
6 · The paper itselfAbstract
Helicase POLQ-like (HELQ) is a DNA helicase essential for the maintenance of genome stability. A recent study identified two HELQ missense mutations in some cases of infertile men. However, the functions of HELQ in the process of germline specification are not well known and whether its function is conserved between mouse and human remains unclear. Here, we revealed that Helq knockout (Helq
Indexed as
Germ CellsAnimalsApoptosisCell DifferentiationDNA HelicasesHumansMaleMiceMice, KnockoutDNA HelicasesHELQ protein, humanHELQ protein, mousegerm cellshelicase POLQ‐likein vitro inductionprimordial germ cell‐like cellsstem cells
Identifiers
PMID38720471
PMCPMC11216937
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390