Evidence map›Paper›PMID 38720351›Full record

ArticleJournal of medical case reports2024

Carbon ion radiotherapy for mesonephric adenocarcinoma of the uterine cervix: a case report.

Nao Kobayashi, Takahiro Oike, Ken Ando, Kazutoshi Murata, Tomoaki Tamaki, Shin-Ei Noda, Kayoko Kogure, Sumihito Nobusawa, Tetsunari Oyama, Tatsuya Ohno

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nao KobayashiDepartment of Radiation Oncology, Kyorin University, 6-20-2 Shinkawa, Mitaka-Shi, Tokyo, 181-8611, Japan. m10201207@gunma-u.ac.jp.
Takahiro OikeDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22 Showa-Machi, Maebashi-Shi, Gunma, 371-8511, Japan.
Ken AndoDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22 Showa-Machi, Maebashi-Shi, Gunma, 371-8511, Japan.
Kazutoshi MurataQST Hospital, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage-Ku, Chiba-Shi, Chiba, 263-8555, Japan.
Tomoaki TamakiDepartment of Radiation Oncology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima-Shi, Fukushima, 960-1295, Japan.
Shin-Ei NodaDepartment of Radiation Oncology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka-Shi, Saitama, 350-1298, Japan.
Kayoko KogureDepartment of Obstetrics and Gynecology, Isesaki Municipal Hospital, 12-1 Tsunatorihonmachi, Isesaki-Shi, Gunma, 372-0817, Japan.
Sumihito NobusawaDepartment of Human Pathology, Gunma University Graduate School of Medicine, 3-39-22 Showa-Machi, Maebashi-Shi, Gunma, 371-8511, Japan.
Tetsunari OyamaDepartment of Diagnostic Pathology, Gunma University Graduate School of Medicine, 3-39-22 Showa-Machi, Maebashi-Shi, Gunma, 371-8511, Japan.
Tatsuya OhnoDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22 Showa-Machi, Maebashi-Shi, Gunma, 371-8511, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMesonephric adenocarcinoma is an extremely rare subtype of uterine cervical cancer that is associated with a poor prognosis and for which a standardized treatment protocol has not been established. Carbon ion radiotherapy (CIRT) is an emerging radiotherapy modality that has been shown to have a favorable anti-tumor effect, even for tumors resistant to conventional photon radiotherapy or chemotherapy. However, there is no report on CIRT outcomes for mesonephric adenocarcinoma of the uterine cervix. CASE PRESENTATION: We treated a 47-year-old Japanese woman with mesonephric adenocarcinoma of the uterine cervix (T2bN0M0 and stage IIB according to the 7th edition of the Union for International Cancer Control and International Federation of Gynecology and Obstetrics, respectively) with CIRT combined with brachytherapy and concurrent chemotherapy. CIRT consisted of whole pelvic irradiation and boost irradiation to the gross tumor; 36.0 Gy (relative biological effectiveness [RBE]) in 12 fractions and 19.2 Gy (RBE) in 4 fractions, respectively, performed once a day, four times per week. Computed tomography-based image-guided adaptive brachytherapy was performed after completion of CIRT, for which the D

conclusionsThis is the first report of CIRT for treatment of mesonephric adenocarcinoma of the uterine cervix. The present case indicates the potential efficacy of CIRT in combination with brachytherapy for treatment of this disease.

Indexed as

AdenocarcinomaBrachytherapyHeavy Ion RadiotherapyUterine Cervical NeoplasmsChemoradiotherapyFemaleHumansMiddle AgedTreatment OutcomeCarbon ion radiotherapyCase reportImage-guided adaptive brachytherapyLung metastasesMesonephric adenocarcinomaUterine cervical cancer

Identifiers

PMID38720351
PMCPMC11080269

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.