Evidence map›Paper›PMID 38720238›Full record

ArticleAnimal models and experimental medicine2024

Characterization of distinct microbiota associated with androgenetic alopecia patients treated and untreated with platelet-rich plasma (PRP).

Qian Zhang, Yanan Wang, Cheng Ran, Yingmei Zhou, Zigang Zhao, Tianhua Xu, Hongwei Hou, Yuan Lu

Abstract read
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Article in Animal models and experimental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. The Disturbed Microbial Niches of Itchy Scalp.Journal of cosmetic dermatology · 2025
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  5. Article
4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Qian ZhangBeijing Life Science Academy, Beijing, China.
Yanan WangDepartment of Pathology, Affiliated Hospital of Hebei University, Baoding, China.
Cheng RanDepartment of Otolaryngology, Affiliated Hospital of Hebei University, Baoding, China.
Yingmei ZhouDepartment of Dermatology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Zigang ZhaoDepartment of Dermatology, Hainan Hospital of PLA General Hospital, Sanya, China.
Tianhua XuDepartment of Otolaryngology, Affiliated Hospital of Hebei University, Baoding, China.
Hongwei HouBeijing Life Science Academy, Beijing, China.
Yuan LuDepartment of Dermatology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.

Funding

Guangdong Enterprise Joint Fund 2022A1515220137Internal project of Huazhong University of Science and Technology Union Shenzhen Hospital YN2021042Internal project of Huazhong University of Science and Technology Union Shenzhen Hospital YN2021045The Shenzhen Science and Technology Innovation Committee JCYJ20220530141615035
6 · The paper itself

Abstract

backgroundAndrogenic alopecia (AGA) is the most common type of hair loss in men, and there are many studies on the treatment of hair loss by platelet-rich plasma (PRP). The human scalp contains a huge microbiome, but its role in the process of hair loss remains unclear, and the relationship between PRP and the microbiome needs further study. Therefore, the purpose of this study was to investigate the effect of PRP treatment on scalp microbiota composition.

methodsWe performed PRP treatment on 14 patients with AGA, observed their clinical efficacy, and collected scalp swab samples before and after treatment. The scalp microflora of AGA patients before and after treatment was characterized by amplifying the V3-V4 region of the 16 s RNA gene and sequencing for bacterial identification.

resultsThe results showed that PRP was effective in the treatment of AGA patients, and the hair growth increased significantly. The results of relative abundance analysis of microbiota showed that after treatment, g_Cutibacterium increased and g_Staphylococcus decreased, which played a stable role in scalp microbiota. In addition, g_Lawsonella decreased, indicating that the scalp oil production decreased after treatment.

conclusionsThe findings suggest that PRP may play a role in treating AGA through scalp microbiome rebalancing.

Indexed as

AlopeciaMicrobiotaPlatelet-Rich PlasmaScalpAdultHumansMaleMiddle AgedYoung Adultandrogenic alopeciamicrobiomeplatelet‐rich plasmascalp

Identifiers

PMID38720238
PMCPMC11079158

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