Evidence map›Paper›PMID 38719903›Full record

ArticleScientific reports2024

Serum iron level is independently associated with sarcopenia: a retrospective study.

Meiying Huang, Bingqing Xu, Yihui Xu, Kaiyu Zhang, Wenyu Zhu, Xiaoyi Lian, Zhe Chen, Minhong Wang, Lei Liu, Zhengli Guo

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Meiying Huang *Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Bingqing Xu *Department of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, 215300, Jiangsu, China.
Yihui XuDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, 215300, Jiangsu, China.
Kaiyu ZhangDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, 215300, Jiangsu, China.
Wenyu ZhuDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, 215300, Jiangsu, China.
Xiaoyi LianDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, 215300, Jiangsu, China.
Zhe ChenLaboratory of Cough, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, Jiangsu, China.
Minhong WangDepartment of Gerontology, Suzhou Municipal Hospital, Suzhou, 215300, Jiangsu, China.
Lei LiuDepartment of Gerontology, Suzhou Municipal Hospital, Suzhou, 215300, Jiangsu, China. pumch-liver@hotmail.com.
Zhengli GuoDepartment of Gerontology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, 215300, Jiangsu, China. 350834416@qq.com.

Funding

Jiangsu Elderly Health Research Project LKM2022058Kunshan Science and Technology Project KS21934Kunshan Science and Technology Project KS2205Kunshan Science and Technology Project KSF202129Science and Technology Project of Suzhou Health Commission LCZX201911
6 · The paper itself

Abstract

Sarcopenia greatly reduces the quality of life of the elderly, and iron metabolism plays an important role in muscle loss. This study aimed to investigate the association between iron status and sarcopenia. A total of 286 adult patients hospitalized between 2019 and 2021 were included in this study, of which 117 were diagnosed with sarcopenia. Serum iron, total iron binding capacity (TIBC), transferrin, and transferrin saturation levels were compared between groups with and without sarcopenia and were included in the logistic analyses, with significant variables further included in the logistic regression model for the prediction of sarcopenia. Serum iron, TIBC, and transferrin levels decreased significantly in the sarcopenia group (p < 0.05), and were negatively associated with handgrip strength, relative skeletal muscle index, and multiple test performances (p < 0.05). Multivariate logistic analysis showed that sex, age, body mass index (BMI), and serum iron level were independent risk factors for sarcopenia. In the final logistic regression model, male sex (odds ratio [OR] 3.65, 95% confidence interval [CI] 1.67-7.98), age > 65 years (OR 5.40, 95% CI 2.25-12.95), BMI < 24 kg/m

Indexed as

IronSarcopeniaTransferrinAgedAged, 80 and overBody Mass IndexFemaleHand StrengthHumansLogistic ModelsMaleMiddle AgedMuscle, SkeletalRetrospective StudiesRisk FactorsIronTransferrin

Identifiers

PMID38719903
PMCPMC11078979

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.