Evidence map›Paper›PMID 38719901›Full record

ArticleScientific reports2024

Identification of master regulator genes controlling pathogenic CD4

José M Jiménez, J Sebastián Contreras-Riquelme, Pía M Vidal, Carolina Prado, Macarena Bastías, Claudio Meneses, Alberto J M Martín, Tomás Perez-Acle, Rodrigo Pacheco

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Intestinal CD4Molecular medicine reports · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

José M Jiménez *Centro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida, Avenida Del Valle Norte #725, 8580702, Huechuraba, Santiago, Chile.
J Sebastián Contreras-Riquelme *Centro de Biotecnología Vegetal, Universidad Andrés Bello, Santiago, Chile.
Pía M VidalBiomedical Science Research Laboratory, Neuroimmunology and Regeneration of the Central Nervous System Unit, Basic Sciences Department, Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepción, Chile.
Carolina PradoCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida, Avenida Del Valle Norte #725, 8580702, Huechuraba, Santiago, Chile.
Macarena BastíasFacultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Claudio MenesesFacultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Alberto J M MartínCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida, Avenida Del Valle Norte #725, 8580702, Huechuraba, Santiago, Chile.
Tomás Perez-AcleCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida, Avenida Del Valle Norte #725, 8580702, Huechuraba, Santiago, Chile.
Rodrigo PachecoCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida, Avenida Del Valle Norte #725, 8580702, Huechuraba, Santiago, Chile. rpacheco@cienciavida.org.ORCID 0000-0001-8057-9806

Funding

Agencia Nacional de Investigación y Desarrollo FB210008Fondo Nacional de Desarrollo Científico y Tecnológico 1210013Fondo Nacional de Desarrollo Científico y Tecnológico 1220196Fondo Nacional de Desarrollo Científico y Tecnológico 3220328Fondo Nacional de Desarrollo Científico y Tecnológico 3220673
6 · The paper itself

Abstract

Inflammatory bowel diseases (IBD) are a group of chronic inflammatory conditions of the gastrointestinal tract associated with multiple pathogenic factors, including dysregulation of the immune response. Effector CD4

Indexed as

CD4-Positive T-LymphocytesGene Regulatory NetworksInflammatory Bowel DiseasesAnimalsDisease Models, AnimalGene Expression RegulationMiceMice, Inbred C57BLMice, KnockoutT-Lymphocytes, RegulatoryCD4+ T cellsGut inflammationInflammatory bowel diseasesMaster regulator genes, Lef1, Mybl2

Identifiers

PMID38719901
PMCPMC11078927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.