ArticleScientific reports2024
Post-intensive care syndrome and health-related quality of life in long-term survivors of cardiac arrest: a prospective cohort study.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prevalence and incidence of post-intensive care syndrome among intensive care unit survivors: a systematic review and meta-analysis.Annals of medicine · 2026Pooled it
- Factors influencing long-term health-related quality of life among intensive care unit survivors: a mixed-methods systematic review.Frontiers in public health · 2026Pooled it
- Pooled it
- Checklist-Guided Code Status Discussions in Patients for Whom Cardiopulmonary Resuscitation Is Considered Futile: An Analysis of a Randomized Clinical Trial.JAMA network open · 2025Trial
- Effects of High-Intensity Interval Training on Cardiopulmonary Function in Patients with Acute Myocardial Infarction with and without Cardiac Arrest: A Retrospective Study.International journal of general medicine · 2026Article
- Supporting Post-ICU Recovery: A Narrative Review for General Practitioners.Diseases (Basel, Switzerland) · 2025Review
- The Prognosis After Cardiac Arrest: Evidence on the Short- and Long-Term Course.Deutsches Arzteblatt international · 2025Review
- Sex disparities in ICU care and outcomes after cardiac arrest: a Swiss nationwide analysis.Critical care (London, England) · 2025Article
- Psychological and behavioral dimensions in cardiac arrest survivors and their families: A state-of-the-art review.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- The interactivity and independence of Recovery challenges and coping strategies for ICU survivors and their caregivers: a systematic review and Meta-synthesis.BMC nursing · 2024Article
- Risk factors of long-term brain health outcomes after hospitalization for critical illness.Journal of neurology · 2024Observational
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Patients discharged from intensive care are at risk for post-intensive care syndrome (PICS), which consists of physical, psychological, and/or neurological impairments. This study aimed to analyze PICS at 24 months follow-up, to identify potential risk factors for PICS, and to assess health-related quality of life in a long-term cohort of adult cardiac arrest survivors. This prospective cohort study included adult cardiac arrest survivors admitted to the intensive care unit of a Swiss tertiary academic medical center. The primary endpoint was the prevalence of PICS at 24 months follow-up, defined as impairments in physical (measured through the European Quality of Life 5-Dimensions-3-Levels instrument [EQ-5D-3L]), neurological (defined as Cerebral Performance Category Score > 2 or Modified Rankin Score > 3), and psychological (based on the Hospital Anxiety and Depression Scale and the Impact of Event Scale-Revised) domains. Among 107 cardiac arrest survivors that completed the 2-year follow-up, 46 patients (43.0%) had symptoms of PICS, with 41 patients (38.7%) experiencing symptoms in the physical domain, 16 patients (15.4%) in the psychological domain, and 3 patients (2.8%) in the neurological domain. Key predictors for PICS in multivariate analyses were female sex (adjusted odds ratio [aOR] 3.17, 95% CI 1.08 to 9.3), duration of no-flow interval during cardiac arrest (minutes) (aOR 1.17, 95% CI 1.02 to 1.33), post-discharge job-loss (aOR 31.25, 95% CI 3.63 to 268.83), need for ongoing psychological support (aOR 3.64, 95% CI 1.29 to 10.29) or psychopharmacologic treatment (aOR 9.49, 95% CI 1.9 to 47.3), and EQ-visual analogue scale (points) (aOR 0.88, 95% CI 0.84 to 0.93). More than one-third of cardiac arrest survivors experience symptoms of PICS 2 years after resuscitation, with the highest impairment observed in the physical and psychological domains. However, long-term survivors of cardiac arrest report intact health-related quality of life when compared to the general population. Future research should focus on appropriate prevention, screening, and treatment strategies for PICS in cardiac arrest patients.
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