Evidence map›Paper›PMID 38719848›Full record

ArticleScientific reports2024

CSC

Rafael Carneiro Ortiz, Nádia Ghinelli Amôr, Luciana Mieli Saito, Mariana Rodrigues Santesso, Nathália Martins Lopes, Rodrigo Fonseca Buzo, Angélica Cristina Fonseca, Gleyson Kleber Amaral-Silva, Raquel Ajub Moyses, Camila Oliveira Rodini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rafael Carneiro OrtizDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil. rafaelortiz@usp.br.
Nádia Ghinelli AmôrDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.
Luciana Mieli SaitoDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.
Mariana Rodrigues SantessoDepartment of Surgery and Orthopedics, Faculty of Medicine, São Paulo State University (UNESP), Botucatu, São Paulo, 18618-687, Brazil.
Nathália Martins LopesDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.
Rodrigo Fonseca BuzoDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.
Angélica Cristina FonsecaDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.
Gleyson Kleber Amaral-SilvaDepartment of Oral Pathology, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Raquel Ajub MoysesDepartment of Head and Neck Surgery, LIM28, Clinical Hospital HCFMUSP, School of Medicine, University of São Paulo, São Paulo, Brazil.
Camila Oliveira RodiniDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil. carodini@usp.br.

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2009/53839-2Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/07245-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/06945-2
6 · The paper itself

Abstract

Identifying marker combinations for robust prognostic validation in primary tumour compartments remains challenging. We aimed to assess the prognostic significance of CSC markers (ALDH1, CD44, p75NTR, BMI-1) and E-cadherin biomarkers in OSCC. We analysed 94 primary OSCC and 67 metastatic lymph node samples, including central and invasive tumour fronts (ITF), along with clinicopathological data. We observed an increase in ALDH1

Indexed as

Aldehyde Dehydrogenase 1 FamilyBiomarkers, TumorCadherinsCarcinoma, Squamous CellMouth NeoplasmsAdultAgedFemaleHumansHyaluronan ReceptorsImmunohistochemistryLymphatic MetastasisMaleMiddle AgedNeoplastic Stem CellsNerve Tissue ProteinsAldehyde Dehydrogenase 1 FamilyALDH1A1 protein, humanBiomarkers, TumorCadherinsCD44 protein, humanHyaluronan ReceptorsNerve Tissue ProteinsNGFR protein, humanPolycomb Repressive Complex 1Receptors, Nerve Growth FactorRetinal DehydrogenaseCancer stem cellsDigital pathologyEpithelial-mesenchymal transitionImmunohistochemistryMetastasisOral cancer

Identifiers

PMID38719848
PMCPMC11078993

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.