Evidence map›Paper›PMID 38719748›Full record

ArticleLife science alliance2024

Molecular mechanism for recognition of the cargo adapter Rab6

Xiaoxin Zhao, Sebastian Quintremil, Estrella D Rodriguez Castro, Heying Cui, David Moraga, Tingyao Wang, Richard B Vallee, Sozanne R Solmaz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoxin ZhaoDepartment of Chemistry, Binghamton University, Binghamton, NY, USA.
Sebastian QuintremilDepartment of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
Estrella D Rodriguez CastroDepartment of Chemistry, Binghamton University, Binghamton, NY, USA.ORCID 0009-0001-5545-5470
Heying CuiDepartment of Chemistry, Binghamton University, Binghamton, NY, USA.
David MoragaDepartment of Chemistry, Binghamton University, Binghamton, NY, USA.ORCID 0000-0003-1504-9109
Tingyao WangDepartment of Chemistry, Binghamton University, Binghamton, NY, USA.
Richard B ValleeDepartment of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
Sozanne R SolmazDepartment of Chemistry, Binghamton University, Binghamton, NY, USA ssolmaz@binghamton.edu.ORCID 0000-0002-1703-3701

Funding

Chemical Approaches to Control the Function of Regulatory RNAsR35GM130207 · NIGMS · STATE UNIVERSITY OF NY,BINGHAMTON · PI ERIKS ROZNERS · 2019 to 2026
$3.7M
Molecular Structural Basis of Non-specific Neuronal Membrane Disruption Induced by Early-Stage Beta-Amyloid Peptide AggregationR01GM125853 · NIGMS · STATE UNIVERSITY OF NY,BINGHAMTON · PI Wei Qiang · 2018 to 2026
$2.5M
Regulation of bidirectional transport of the nucleus by adapter proteinsR01GM144578 · NIGMS · STATE UNIVERSITY OF NY,BINGHAMTON · PI SOLMAZ, SOZANNE R · 2022 to 2025
$1.6M
NIGMS NIH HHS R01 GM125853NIGMS NIH HHS R01 GM144578NIGMS NIH HHS R35 GM130207
6 · The paper itself

Abstract

Rab6 is a key modulator of protein secretion. The dynein adapter Bicaudal D2 (BicD2) recruits the motors cytoplasmic dynein and kinesin-1 to Rab6

Indexed as

DyneinsProtein Bindingrab GTP-Binding ProteinsBinding SitesGuanosine TriphosphateHumansKinesinsMicrotubule-Associated ProteinsModels, MolecularMutationProtein TransportBICD2 protein, humanDyneinsGuanosine TriphosphateKinesinsMicrotubule-Associated ProteinsRab6 proteinrab GTP-Binding Proteins

Identifiers

PMID38719748
PMCPMC11077774

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.