Evidence map›Paper›PMID 38719718›Full record

ArticleHematology, transfusion and cell therapy2024

Evaluation of blood cell count using an automatic hematology analyzer to optimize collection of peripheral blood progenitor cells by leukapheresis.

Paula Renata Machado Passos Pederzoli, Karen de Lima Prata, Nathália Gomide Cruz, Pedro Victorio de Almeida Marzano, Maurício Colombini Martins, Luciana de Almeida Costa, Roberta Kelly de Andrade, Marcia Regina Issa Salomão Libânio, Brian Custer, André Rolim Belisário

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In one paragraph

Article in Hematology, transfusion and cell therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paula Renata Machado Passos PederzoliCentro de Tecidos Biológicos de Minas Gerais, Fundação Hemominas, Rua das Goiabeiras, 779, Lagoa Santa, Minas Gerais 33400-000, Brazil.
Karen de Lima PrataCentro de Tecidos Biológicos de Minas Gerais, Fundação Hemominas, Rua das Goiabeiras, 779, Lagoa Santa, Minas Gerais 33400-000, Brazil.
Nathália Gomide CruzFundação Hemominas, Alameda Ezequiel Dias, 321, Belo Horizonte, Minas Gerais 30130-110, Brazil.
Pedro Victorio de Almeida MarzanoCentro de Tecidos Biológicos de Minas Gerais, Fundação Hemominas, Rua das Goiabeiras, 779, Lagoa Santa, Minas Gerais 33400-000, Brazil.
Maurício Colombini MartinsCentro de Tecidos Biológicos de Minas Gerais, Fundação Hemominas, Rua das Goiabeiras, 779, Lagoa Santa, Minas Gerais 33400-000, Brazil.
Luciana de Almeida CostaCentro de Tecidos Biológicos de Minas Gerais, Fundação Hemominas, Rua das Goiabeiras, 779, Lagoa Santa, Minas Gerais 33400-000, Brazil.
Roberta Kelly de AndradeCentro de Tecidos Biológicos de Minas Gerais, Fundação Hemominas, Rua das Goiabeiras, 779, Lagoa Santa, Minas Gerais 33400-000, Brazil.
Marcia Regina Issa Salomão LibânioSecretaria de Estado da Saúde de Minas Gerais, Cidade Administrativa, Edifício Minas, 12º andar, Rod. Papa João Paulo II - Serra Verde, Belo Horizonte, Minas Gerais 31585-200, Brazil.
Brian CusterVitalant Research Institute, 360 Spear St Suite 200, San Francisco, CA 94105, USA; Department of Laboratory Medicine, UCSF. 185 Berry Street, Suite 100, Box 0134, San Francisco, CA 94143-0134, USA.
André Rolim BelisárioCentro de Tecidos Biológicos de Minas Gerais, Fundação Hemominas, Rua das Goiabeiras, 779, Lagoa Santa, Minas Gerais 33400-000, Brazil. Electronic address: andre.belisario@hemominas.mg.gov.br.

Funding

International Traineeships in AIDS Prevention Studies (ITAPS)R25MH123256 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTINA P LINDAN · 2020 to 2026
$1.8M
NIMH NIH HHS R25 MH123256
6 · The paper itself

Abstract

backgroundAutologous stem cell transplantation is a treatment modality for several diseases. Prediction of successful mobilization may be useful to optimize hematopoietic stem cell collection. STUDY DESIGN AND

methodsThis was a retrospective study with data from transplantation candidates between September 2015 and December 2021 being analyzed. The medical record of each patient was reviewed to mine mobilization information. The laboratory data analyzed were CD34

resultsThis study included 807 patients. Increased patient weight, low mean corpuscular volume, high nucleated red blood cells, peripheral blood mononuclear cell and immature granulocyte counts were significantly associated with good mobilization. In addition, patients diagnosed with multiple myeloma were two times more likely to be good mobilizers than patients with lymphoma. The model was applied to a validation set to identify patients who underwent apheresis (CD34

conclusionSuccess in mobilization was greater in patients who underwent the first mobilization cycle and who had a diagnosis of multiple myeloma. Furthermore, higher body weight, and nucleated red blood cells, immature granulocytes and mononuclear cell counts, as well as low mean corpuscular volumes, were associated with successful mobilization.

Indexed as

ApheresisCD34(+) enumerationGood mobilizersPBSC collectionStem cell transplantation

Identifiers

PMID38719718
PMCPMC11726100

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.