Type 1 Diabetes Mellitus with Diabetic Ketoacidosis Presenting with Transient Severe Fatty Liver and Subsequent Liver Dysfunction.

Takayuki Suzuki, Kazuki Orime, Ryoichi Akamatsu, Tomoaki Akiyama, Tadashi Yamakawa, Yasuo Terauchi

Abstract readCase Reports

In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Takayuki SuzukiDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Japan.

Kazuki OrimeDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Japan.

Ryoichi AkamatsuDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Japan.

Tomoaki AkiyamaDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Japan.

Tadashi YamakawaDepartment of Endocrinology and Diabetes, Yokohama City University Medical Center, Japan.

Yasuo TerauchiDepartment of Endocrinology and Metabolism, Yokohama City University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients often present with severe fatty liver (FL) due to insulin deficiency at the onset of diabetic ketoacidosis (DKA). On the other hand, glycogenic hepatopathy (GH) is a possible cause of liver dysfunction in patients with DKA. We herein report a case of type 1 diabetes mellitus with severe FL at the onset of DKA, who demonstrated subsequent marked liver dysfunction after achieving an improvement of FL. As liver dysfunction persisted even after the FL improved, GH was suspected to be the cause of liver dysfunction. FL and GH have different prognoses and should therefore be differentiated using imaging studies and biopsies.

Indexed as

Diabetes Mellitus, Type 1Diabetic KetoacidosisFatty LiverHumansSeverity of Illness Indexdiabetic ketoacidosisfatty liverglycogenic hepatopathy

Identifiers

PMID38719597

DOI10.2169/internalmedicine.3488-24

PMCPMC11729162

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