ArticlePhysical activity and nutrition2024
Role of exercise in modulating prefrontal cortical activation for improved gait and cognition in Parkinson's disease patients.
Article in Physical activity and nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Brain markers of cognitive-motor control of gait function in Parkinson's disease: links with physical activity and aerobic fitness.Physical activity and nutrition · 2026Article
- Structural and functional brain changes following diverse exercise interventions in Parkinson's disease: an MRI-based narrative review.Physical activity and nutrition · 2026Article
- Speed-Variable Treadmill Training Improves Hand Motor Function in Individuals With Parkinson's Disease.Parkinson's disease · 2026Article
- Cerebral activation following dynamic cycling in individuals with and without Parkinson's disease: an fNIRS investigation.Frontiers in human neuroscience · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
purposeThis narrative review evaluated the impact of exercise on gait and cognitive functions in patients with Parkinson's disease (PD), focusing on prefrontal cortical (PFC) activation assessed using near-infrared spectroscopy (NIRS).
methodsA literature search was conducted in the PubMed and Web of Science databases using keywords such as "Parkinson's disease," "gait," "cognitive functions," "exercise," and "NIRS," focusing on publications from the last decade. Studies measuring PFC activity using NIRS during gait tasks in patients with PD were selected.
resultsThe review indicated that patients with PD demonstrate increased PFC activity during gait tasks compared to healthy controls, suggesting a greater cognitive demand for movement control. Exercise has been shown to enhance neural efficiency, thus improving gait and cognitive functions.
conclusionExercise is crucial for improving gait and cognitive functions in patients with PD through increased PFC activation. This emphasizes the importance of incorporating exercise into PD management plans and highlights the need for further studies on its long-term effects and the neurobiological mechanisms underlying its benefits, with the aim of optimizing therapeutic strategies and improving patients' quality of life.
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Registered trials
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