Evidence map›Paper›PMID 38719444›Full record

ArticleJournal of neurointerventional surgery2024

Comparison of Pipeline embolization device versus Tubridge embolization device in unruptured intracranial aneurysms: a multicenter, propensity score matched study.

Chi Huang, Gengwu Ma, Xin Tong, Xin Feng, Zhuohua Wen, Mengshi Huang, Anqi Xu, Hao Yuan, HongYu Shi, Jiancheng Lin and 14 more

Registry-linked trialAbstract readMulticenter StudyComparative Study
In one paragraph

Article in Journal of neurointerventional surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06308952 (Atorvastatin Pretreatment in Cerebrovascular Events), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06308952 phase4recruitingnot on this map

Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation: Protocol of a Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial

TypeinterventionalSponsorDuan ChuanzhiRan2024 to 2027Enrolled354ConditionsCerebrovascular Event, Stent Stenosis, Ischemic Stroke, Hemorrhagic StrokeArmsAtorvastatin 20mg
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Chi Huang *Neurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.ORCID http://orcid.org/0009-0003-9134-3921
Gengwu Ma *Neurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Xin TongNeurointervention Center, Beijing Neurosurgical Institute, Beijing, Beijing, China.ORCID http://orcid.org/0000-0002-4893-1299
Xin FengNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.ORCID http://orcid.org/0000-0002-4874-8048
Zhuohua WenNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Mengshi HuangNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Anqi XuNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Hao YuanNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
HongYu ShiNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.ORCID http://orcid.org/0009-0009-8488-0685
Jiancheng LinNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Can LiNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Runze GeNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Jiwan HuangNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Chao PengDepartment of Neurosurgery, Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China.
Yajun ZhuDepartment of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.ORCID http://orcid.org/0000-0001-9153-9930
Tao WangDepartment of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Southwest Medical University, Luzhou, Sichuan, China.
Changren HuangDepartment of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Southwest Medical University, Luzhou, Sichuan, China.
Zongduo GuoDepartment of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Shuyin LiangNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Shixing SuNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Xin ZhangNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Xifeng LiNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Aihua LiuNeurointervention Center, Beijing Neurosurgical Institute, Beijing, Beijing, China doctor_duanZJ@163.com liuaihuadoctor@163.com.ORCID http://orcid.org/0000-0002-6391-805X
Chuan-Zhi DuanNeurosurgery Center, Department of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China doctor_duanZJ@163.com liuaihuadoctor@163.com.ORCID http://orcid.org/0000-0003-2614-0418

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFlow diverter devices (FDs) are increasingly used for treating unruptured intracranial aneurysms (UIAs), but limited studies compared different FDs.

objectiveTo conduct a propensity score matched analysis comparing the Pipeline embolization device (PED) and Tubridge embolization device (TED) for UIAs.

methodsPatients with UIAs treated with either PED or TED between July 2016 and July 2022 were included. Propensity score matching was performed to adjust for age, sex, comorbidities, smoking, drinking, aneurysm size, morphology, neck, location, parent artery diameter, adjunctive coiling, and angiographic follow-up duration. Perioperative complications and clinical and angiographic outcomes were compared after matching.

results735 patients treated by PED and 290 patients treated by TED were enrolled. Compared with the PED group, patients in the TED group had a greater number of women and patients with ischemia, a smaller proportion of vertebrobasilar and non-saccular aneurysms, a smaller size and neck, and fewer adjunctive coils and overlapping stents, but a larger parent artery diameter and lumen disparities. After adjusting for these differences, 275 pairs were matched. No differences were found in perioperative complications (4.4% vs 2.5%, P=0.350), in-stent stenosis (16.0% vs 15.6%, P>0.999), or favorable prognosis (98.9% vs 98.5%, P>0.999). However, PED showed a trend towards better complete occlusion over a median 8-month angiographic follow-up (81.8% vs 75.3%, P=0.077).

conclusionCompared with PED, TED provides a comparable rate of perioperative and short-term outcomes. Nevertheless, a better occlusion status in the PED group needs to be further verified over a longer follow-up period.

Indexed as

Embolization, TherapeuticIntracranial AneurysmAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesStentsTreatment OutcomeAneurysmFlow DiverterVascular Malformation

Identifiers

PMID38719444
PMCPMC12015021

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.