Evidence map›Paper›PMID 38718234›Full record

ArticleWMJ : official publication of the State Medical Society of Wisconsin2024

Same People, Different Results: Categorizing Cancer Registry Cases Across the Rural-Urban Continuum.

Andrea M Schiefelbein, John K Krebsbach, Amy K Taylor, Amy K Haimson, Patrick R Varley, Melissa C Skala, John M Eason, Noelle K LoConte

Abstract read
In one paragraph

Article in WMJ : official publication of the State Medical Society of Wisconsin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Urban-rural differences in cancer mortality: Operationalizing rurality.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrea M SchiefelbeinMorgridge Institute for Research, Madison, Wisconsin.
John K KrebsbachUniversity of Wisconsin-Madison, Madison, Wisconsin.
Amy K TaylorDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Amy K HaimsonDepartment of Sociology, University of Wisconsin-Madison, Madison, Wisconsin.
Patrick R VarleyDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Melissa C SkalaMorgridge Institute for Research, Madison, Wisconsin.
John M EasonDepartment of Sociology, University of Wisconsin-Madison, Madison, Wisconsin.
Noelle K LoConteDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, Ns3@medicine.wisc.edu.ORCID 0000-0002-3883-4153

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
Optical imaging of pancreas cancer organoids for drug development and personalized treatmentR01CA211082 · NCI · MORGRIDGE INSTITUTE FOR RESEARCH, INC. · PI SKALA, MELISSA CAROLINE · 2017 to 2021
$3.5M
Cellular-level Optical Metabolic Imaging to Predict Drug Response in CancerR01CA185747 · NCI · VANDERBILT UNIVERSITY · PI SKALA, MELISSA CAROLINE · 2014 to 2019
$1.6M
NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA185747NCI NIH HHS R01 CA211082
6 · The paper itself

Abstract

backgroundMany rural-urban indexes are utilized in cancer research. This variation introduces inconsistencies between studies. Recommendations on index use have prioritized geographical unit over feasibility of inclusion in analysis. We evaluated rural-urban indexes and recommend one for use to increase comparability across studies.

methodsWe assessed 9 US rural-urban indexes regarding their respective rural and urban code ranges; geographical unit, land area, and population distributions; percent agreement; suitability for analysis; and integration feasibility for national, state, and local cancer research. We referenced 1569 Wisconsin Pancreatic Cancer Registry patients to demonstrate how index choice affects patient categorization.

resultsSix indexes categorized rural and urban areas. Indexes agreed on binary rural-urban designation for 88.8% of the US population. As ternary variables, they agreed for 83.4%. For cancer registry patients, this decreased to 73.4% and 60.4% agreement, respectively. Rural-Urban Continuum Codes (RUCC) performed the best in differentiating metropolitan, micropolitan, and rural counties; availability for retrospective and prospective studies; and continuous coding for analysis.

conclusionsUrban/rural patient categorization changed with index selection. We conclude that RUCC is an appropriate and feasible rural-urban index to include in cancer research, as it is standardly available in national cancer registries, can be matched to patient's county of residence for local research, and it had the least amount of fluctuation of the indices analyzed. Utilizing RUCC as a continuous variable across studies with a rural-urban component will increase reproducibility and comparability of results and eliminate rural-urban index choice as a potential source of discrepancy between studies.

Indexed as

RegistriesRural PopulationUrban PopulationFemaleHumansMaleNeoplasmsPancreatic NeoplasmsWisconsin

Identifiers

PMID38718234
PMCPMC11406676

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.