ArticleScience advances2024
Flexible circumferential bioelectronics to enable 360-degree recording and stimulation of the spinal cord.
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Surface circumferential spinal cord recording in freely moving rodents.Nature communications · 2026Article
- Active devices and systems for closed-loop neuromodulation.Microsystems & nanoengineering · 2026Review
- PEDOT: PSS for Implantable and Wearable Bioelectronics: From Material Engineering and Energy Storage to Clinical Translation.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Strain resilient and self-healing nanocomposite conductors with ultralow sheet resistance.Nature communications · 2026Article
- Customized ultra-flexible and adhesive spinal cord stimulation electrode for chronic pain management.Materials today. Bio · 2026Article
- Morphology-adaptive Au-Ag nanowire elastronics for integrated FlexoSERS and bioelectrical sensing.Science advances · 2026Article
- PEDOT:PSS-A Key Material for Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Conformable thin-film cuff electrodes as tools for peripheral nerve recording: a comparative study.Frontiers in neuroscience · 2026Article
- High-resolution imaging and three-dimensional model of the feline spinal cord.Frontiers in neuroanatomy · 2026Article
- Multifunctional Biomedical Devices with Closed-Loop Systems for Precision Therapy.Advanced healthcare materials · 2025Review
- Neuroprosthetic closed-loop strategy for sustained blood pressure reduction via simultaneous stimulation and recording from the spinal cord.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Fabrication of thin-film electrodes and organic electrochemical transistors for neural implants.Nature protocols · 2025Review
- Thermal Processing Creates Water-Stable PEDOT:PSS Films for Bioelectronics.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- An active electronic, high-density epidural paddle array for chronic spinal cord neuromodulation.Journal of neural engineering · 2025Article
- The ins and outs of spinal cord stimulation.Brain communications · 2025Article
- Towards Precise Synthetic Neural Codes: High-dimensional Stimulation with Flexible Electrodes.Npj flexible electronics · 2025Article
- In vivo dynamic tracking of cerebral chloride regulation using molecularly tailored liquid/liquid interfacial ultramicro iontronics.Science advances · 2024Article
- Introductory Review of Soft Implantable Bioelectronics Using Conductive and Functional Hydrogels and Hydrogel Nanocomposites.Gels (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spinal cord is crucial for transmitting motor and sensory information between the brain and peripheral systems. Spinal cord injuries can lead to severe consequences, including paralysis and autonomic dysfunction. We introduce thin-film, flexible electronics for circumferential interfacing with the spinal cord. This method enables simultaneous recording and stimulation of dorsal, lateral, and ventral tracts with a single device. Our findings include successful motor and sensory signal capture and elicitation in anesthetized rats, a proof-of-concept closed-loop system for bridging complete spinal cord injuries, and device safety verification in freely moving rodents. Moreover, we demonstrate potential for human application through a cadaver model. This method sees a clear route to the clinic by using materials and surgical practices that mitigate risk during implantation and preserve cord integrity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.