Evidence map›Paper›PMID 38717931›Full record

Trial reportActa obstetricia et gynecologica Scandinavica2024

A prospective 12-month structured weight loss intervention in women with severe obesity and polycystic ovary syndrome: Impact of weight loss on eating behaviors.

Josefin Kataoka, Elisabet Stener-Victorin, Johanna Schmidt, Ingrid Larsson

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Acta obstetricia et gynecologica Scandinavica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01319162 (To Estimate the Prevalence of PCOS in Obese Premenopausal Women and Elucidate How They Respond to a Weight Reduction Treatment Program), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01319162 completednot on this map

To Estimate the Prevalence of PCOS in Obese Premenopausal Women and Elucidate How They Respond to a Weight Reduction Treatment Program

TypeobservationalSponsorGöteborg UniversityRan2011 to 2017Enrolled300ConditionsPolycystic Ovary SyndromeArmsWeight reduction regimen
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Josefin KataokaInstitute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0003-2465-7309
Elisabet Stener-VictorinDepartment of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden.
Johanna SchmidtInstitute of Clinical Sciences, Sahlgrenska academy, University of Gothenburg, Gothenburg, Sweden.
Ingrid LarssonDepartment of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.

Funding

Diabetesfonden DIA2021-633Göteborgs Läkaresällskap GLS 961123Novo Nordisk Fonden NNF19OC0056647Novo Nordisk Fonden NNF22OC0072904Regional Agreement on Medical Training and Clinical Research between the Stockholm County Council and the Karolinska Institutet ALFMedN 20190079Strategic Research Programme (SRP) in Diabetes at Karolinska InstitutetVetenskapsrådet 2018-02872Vetenskapsrådet 2022-005520
6 · The paper itself

Abstract

introductionThe knowledge regarding eating behavior and disorders in women with polycystic ovary syndrome (PCOS) and severe obesity is limited. This study aimed to assess eating behavior and lifestyle factors in women with severe obesity (BMI ≥35 kg/m MATERIAL AND

methodsA prospective clinical trial with participants screened for PCOS using National Institutes of Health criteria. Participants completed the Food Frequency Questionnaire, International Physical Activity Questionnaire, Three-Factor Eating Questionnaire, and Questionnaire of Eating and Weight Patterns-revised, and were evaluated regarding binge eating disorder using DSM-5 criteria before and after a 12-month weight loss intervention. CLINICALTRIALS: gov: NCT01319162.

results246 women were included (PCOS n = 63, age 33.0 ± 8.4, BMI 39.9 ± 4.7; non-PCOS n = 183, age 37.7 ± 8.7, BMI 39.6 ± 4.3). Women with PCOS showed elevated baseline scores in cognitive restraint eating (50.0 [33.3-63.2]) compared to women without PCOS (38.9 [27.8-55.6]; p = 0.012). No differences were observed between groups in emotional and uncontrolled eating. In both groups, cognitive restraint eating was negatively correlated with energy intake (PCOS: r = -0.315, p < 0.05; non-PCOS: r = -0.214, p < 0.001), while uncontrolled eating displayed a positive correlation with energy intake (PCOS: r = 0.263, p = 0.05; non-PCOS: r = 0.402, p < 0.001). A positive correlation was found between emotional eating and energy intake only in women without PCOS (r = 0.400, p < 0.001). Baseline self-reported energy intake and physical activity did not differ between groups. At 12-month follow-up, women with PCOS reported reduced fat intake. Women without PCOS reported reduced energy intake, carbohydrates and sugar, increased protein, reduced scores for emotional and uncontrolled eating, and heightened scores for cognitive restraint eating. Comparing changes from baseline to follow-up, differences were found between groups in cognitive restraint, intake of fat, carbohydrates, and sugar. The mean weight loss was 12-14 kg, with no between-group difference (p = 0.616).

conclusionsWomen with severe obesity and PCOS showed elevated cognitive restraint eating behaviors compared to women without PCOS. Although significant weight loss was seen in both groups, alterations in eating behavior more favorable for weight loss were only seen in women without PCOS.

Indexed as

Feeding BehaviorPolycystic Ovary SyndromeWeight LossAdultFemaleHumansObesity, MorbidProspective StudiesSurveys and QuestionnairesWeight Reduction Programsdietary intakeeating behaviorobesitypolycystic ovary syndromeweight loss

Identifiers

PMID38717931
PMCPMC11266713

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.