Evidence map›Paper›PMID 38717604›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

A survey of preferences and expectations for surgical interventions targeting atonic seizures in Lennox-Gastaut syndrome.

Evelyn Pan, Martin G Piazza, Robert J Kellogg, Steven Wisniewski, Taylor J Abel

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Evelyn PanDepartment of Neurological Surgery, University of Pittsburgh, 4401 Penn Ave, Fl 4, Pittsburgh, PA, USA.
Martin G PiazzaDepartment of Neurological Surgery, University of Pittsburgh, 4401 Penn Ave, Fl 4, Pittsburgh, PA, USA.
Robert J KelloggDepartment of Neurological Surgery, University of Pittsburgh, 4401 Penn Ave, Fl 4, Pittsburgh, PA, USA.
Steven WisniewskiEpidemiology Data Center, University of Pittsburgh, Pittsburgh, PA, USA.
Taylor J AbelDepartment of Neurological Surgery, University of Pittsburgh, 4401 Penn Ave, Fl 4, Pittsburgh, PA, USA. abeltj@upmc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess preferences and outcome expectations for vagus nerve stimulation (VNS) and corpus callosotomy (CC) surgeries in the treatment of atonic seizure in Lennox-Gastaut syndrome (LGS).

methodsA total of 260 surveys were collected from patients are caregivers of LGS patients via Research Electronic Data Capture (REDCap).

resultsRespondents reported an average acceptable atonic seizure reduction rate of 55.9% following VNS and 74.7% following CC. 21.3% (n = 50) were willing to be randomized. Respondents reported low willingness for randomization and a higher seizure reduction expectation with CC.

conclusionOur findings guide surgical approaches for clinicians to consider patient preference in order to design future studies comparing effectiveness between these two procedures.

Indexed as

Lennox Gastaut SyndromePatient PreferenceVagus Nerve StimulationAdolescentAdultChildChild, PreschoolCorpus CallosumFemaleHumansInfantMaleNeurosurgical ProceduresSeizuresSurveys and QuestionnairesTreatment OutcomeAtonic seizuresLaser ablationPediatric drug-resistant epilepsySeizure outcomes

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.