Evidence map›Paper›PMID 38717592›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2024

Assessment of [

Maria Meindl, Artem Zatcepin, Johannes Gnörich, Maximilian Scheifele, Mirlind Zaganjori, Mattes Groß, Simon Lindner, Rebecca Schaefer, Marcel Simmet, Sebastian Roemer and 11 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Associations of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  2. Dynamic [Molecular neurodegeneration · 2026
    Article
  3. Feasibility of short imaging protocols for [European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Detection of Focal Lesions in Epilepsy with [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  5. Article
  6. Longitudinal monitoring of tau aggregation in progressive supranuclear palsy with [Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  7. Developing a novel reference region for [European journal of nuclear medicine and molecular imaging · 2025
    Article
  8. Kinetic modeling ofEJNMMI research · 2025
    Article
  9. Radiosynthesis,ACS chemical neuroscience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Maria MeindlDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany. maria.meindl@med.uni-muenchen.de.
Artem ZatcepinDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Johannes GnörichDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Maximilian ScheifeleDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Mirlind ZaganjoriDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Mattes GroßDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Simon LindnerDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Rebecca SchaeferDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Marcel SimmetDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Sebastian RoemerDepartment of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Sabrina KatzdoblerDepartment of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Johannes LevinDepartment of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Günter HöglingerGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Ann-Cathrin BischofDepartment of Anesthesiology, LMU University Hospital, LMU Munich, Munich, Germany.
Henryk BarthelDepartment of Nuclear Medicine, University of Leipzig, Leipzig, Germany.
Osama SabriDepartment of Nuclear Medicine, University of Leipzig, Leipzig, Germany.
Peter BartensteinDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Thomas SallerDepartment of Anesthesiology, LMU University Hospital, LMU Munich, Munich, Germany.
Nicolai FranzmeierInstitute for Stroke and Dementia Research (ISD), Munich, Germany.
Sibylle ZieglerDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Matthias BrendelDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.

Funding

Bundesministerium für Bildung und Forschung 01EK1605A HitTauDeutsche Forschungsgemeinschaft EXC 2145 SyNergy - ID 390857198)
6 · The paper itself

Abstract

purpose[

methodsIn the first part of the study, we validated AIF derived from radial artery whole blood against IDIF by investigating 20 subjects (ten controls and ten patients). IDIF were generated by manual extraction of the carotid artery using the average and the five highest (max5) voxel intensity values and by automated extraction of the carotid artery using the average and the maximum voxel intensity value. In the second part of the study, IDIF quantification using the IDIF with the closest match to the AIF was transferred to group comparison of a large independent cohort of 40 subjects (15 healthy controls, 15 PSP patients and 10 AD patients). We compared V

resultsAIF and IDIF showed highly correlated input curves for all applied IDIF extraction methods (0.78 < r < 0.83, all p < 0.0001; area under the curves (AUC): 0.73 < r ≤ 0.82, all p ≤ 0.0003). Regarding the V

conclusionBlood-free IDIF is a promising approach for quantification of [

Indexed as

Alzheimer DiseaseImage Processing, Computer-AssistedPositron-Emission Tomographytau ProteinsAgedAutomationCase-Control StudiesFemaleHumansMaleMiddle AgedRadiopharmaceuticalsSupranuclear Palsy, ProgressiveRadiopharmaceuticalstau Proteins[18F]PI-2620 quantificationAlzheimer’s diseaseFour-repeat tauopathiesImage derived input functionTau

Identifiers

PMID38717592
PMCPMC11368995

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.