Evidence map›Paper›PMID 38717561›Full record

SynthesisHernia : the journal of hernias and abdominal wall surgery2024

The impact of smoking on inguinal hernia repair outcomes: a meta-analysis of multivariable-adjusted studies.

P Marcolin, B Oliveira Trindade, S Bueno Motter, G R Brandão, N Messer, S Mazzola Poli de Figueiredo

Abstract readMeta-AnalysisSystematic Review
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In one paragraph

Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

P MarcolinDivision of Surgery, Federal University of the Southern Border (Universidade Federal da Fronteira Sul), 20 Capitão Araujo St, Passo Fundo, 99010-121, Brazil. Patricia.marcolin@estudante.uffs.edu.br.ORCID 0000-0003-3241-5545
B Oliveira TrindadeDivision of Surgery, Federal University of Health Sciences of Porto Alegre, R. Sarmento Leite, 245 - Centro Histórico, Porto Alegre, RS, 90050-170, Brazil.ORCID 0000-0002-5157-1108
S Bueno MotterDivision of Surgery, Federal University of Health Sciences of Porto Alegre, R. Sarmento Leite, 245 - Centro Histórico, Porto Alegre, RS, 90050-170, Brazil.ORCID 0000-0001-8041-4630
G R BrandãoDivision of Surgery, Federal University of Health Sciences of Porto Alegre, R. Sarmento Leite, 245 - Centro Histórico, Porto Alegre, RS, 90050-170, Brazil.ORCID 0000-0002-7224-0383
N MesserDivision of Surgery, Center for Abdominal Core Health, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
S Mazzola Poli de FigueiredoDivision of Surgery, Center for Abdominal Core Health, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH, 44195, USA.ORCID 0000-0003-2986-8164

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhile the detrimental effects of smoking on postoperative outcomes are recognized, the extent of its risk for inguinal hernia repair remains unclear. Our study aims to assess the influence of smoking on patients who undergo inguinal hernia repair.

methodsWe systematically reviewed PubMed, Embase, and Cochrane databases. Our goal was to identify studies that compared postoperative outcomes in smoking and non-smoking patients after inguinal hernia repair, and which employed a multivariate analysis to reduce possible confounding factors. Outcomes were recurrence, postoperative complications, and surgical site infection. Odds ratios (ORs) with 95% confidence intervals (CIs) were computed with the use of a random-effects model. Heterogeneity was examined with I

resultsOur analysis encompassed 11 studies, involving a total of 577,901 patients. Of these, 77,226 (or 13.4%) identified as smokers, with males constituting 90% of the cohort. In terms of surgical approaches, 58% underwent laparoscopic procedures were most common at 58%, followed by open surgeries at 41%, and 1% used robotic techniques. All included studies had a low risk of bias. Smoking was associated with a higher incidence of hernia recurrence (OR 2.95; 95% CI 2.08 to 4.18; p < 0.001; I2 = 0%). No differences were found in postoperative complication (OR 1.15; 95% CI 1.00 to 1.32; p = 0.05; I2 = 56%) or surgical site infection (OR 2.94; 95% CI 0.80 to 10.88; p = 0.11; I2 = 79%).

conclusionSmoking was associated with a three-fold increase in recurrence. Further studies are needed to evaluate the impact of preoperative smoking cessation on reducing recurrence.

Indexed as

Hernia, InguinalHerniorrhaphyRecurrenceSmokingHumansPostoperative ComplicationsRisk FactorsSurgical Wound InfectionInguinal herniaRecurrenceSmokingSurgical site infection

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.