Evidence map›Paper›PMID 38717427›Full record

ReviewNanomedicine (London, England)2024

Recent advances in nanoformulation-based delivery for cancer immunotherapy.

Seyedeh Saimeh Bokhari, Tayyab Ali, Muhammad Naeem, Fatma Hussain, Abdul Nasir

Abstract readReview
In one paragraph

Review in Nanomedicine (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seyedeh Saimeh BokhariClinico-Molecular Biochemistry Laboratory, Department of Biochemistry, University of Agriculture, 38000, Faisalabad, Pakistan.
Tayyab AliClinico-Molecular Biochemistry Laboratory, Department of Biochemistry, University of Agriculture, 38000, Faisalabad, Pakistan.
Muhammad NaeemCollege of Life Science, Hebei Normal University, Shijiazhuang,  050024, China.ORCID 0000-0002-5078-5470
Fatma HussainClinico-Molecular Biochemistry Laboratory, Department of Biochemistry, University of Agriculture, 38000, Faisalabad, Pakistan.
Abdul NasirMedical Research Center, Second Affiliated Hospital of Zhengzhou University, Zhengzhou,  450000, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the leading causes of mortality worldwide, and its treatment faces several challenges. Phytoconstituents derived from recently discovered medicinal plants through nanotechnology potentially target cancer cells via PI3K/Akt/mTOR pathways and exert their effects selectively through the generation of reactive oxygen species through β-catenin inhibition, DNA damage, and increasing caspase 3/9 and p53 expression. These nanocarriers act specifically against different cancer cell lines such as HT-29, MOLT-4 human leukemia cancer and MCF-7 cell lines SKOV-3, Caov-3, SW-626, HepG2, A-549, HeLa, and MCF-7. This review comprehensively elaborates on the cellular and molecular mechanisms, and therapeutic prospects of various plant-mediated nanoformulations to attain a revolutionary shift in cancer immunotherapy.

Indexed as

ImmunotherapyNeoplasmsAnimalsCell Line, TumorDrug CarriersDrug Delivery SystemsHumansNanoparticlesPlants, MedicinalDrug Carriersanticancerapoptosiscell cyclecytotoxicitymedicinal plantsnanoparticlesreactive oxygen species

Identifiers

PMID38717427
PMCPMC11285355

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.