Evidence map›Paper›PMID 38717292›Full record

ArticleRadiology. Artificial intelligence2024

Performance of an Open-Source Large Language Model in Extracting Information from Free-Text Radiology Reports.

Bastien Le Guellec, Alexandre Lefèvre, Charlotte Geay, Lucas Shorten, Cyril Bruge, Lotfi Hacein-Bey, Philippe Amouyel, Jean-Pierre Pruvo, Gregory Kuchcinski, Aghiles Hamroun

Abstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Bastien Le GuellecFrom the Department of Neuroradiology (B.L.G., A.L., C.B., J.P.P., G.K.), Department of Public Health (B.L.G., P.A., A.H.), and INclude Health Data Warehouse (C.G., L.S.), CHU Lille-Université Lille, Rue Emile Laine, 59000 Lille, France; Department of Radiology, UC Davis Health, Sacramento, Calif (L.H.B.); Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France (P.A., A.H.); INSERM, U1172-LilNCog-Lille Neuroscience & Cognition, Université Lille, Lille, France (J.P.P., G.K.); and UAR 2014-US 41-PLBS-Plateformes Lilloises en Biologie & Santé, Université Lille, Lille, France (J.P.P., G.K.).ORCID 0000-0002-3618-4791
Alexandre LefèvreFrom the Department of Neuroradiology (B.L.G., A.L., C.B., J.P.P., G.K.), Department of Public Health (B.L.G., P.A., A.H.), and INclude Health Data Warehouse (C.G., L.S.), CHU Lille-Université Lille, Rue Emile Laine, 59000 Lille, France; Department of Radiology, UC Davis Health, Sacramento, Calif (L.H.B.); Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France (P.A., A.H.); INSERM, U1172-LilNCog-Lille Neuroscience & Cognition, Université Lille, Lille, France (J.P.P., G.K.); and UAR 2014-US 41-PLBS-Plateformes Lilloises en Biologie & Santé, Université Lille, Lille, France (J.P.P., G.K.).
Charlotte GeayFrom the Department of Neuroradiology (B.L.G., A.L., C.B., J.P.P., G.K.), Department of Public Health (B.L.G., P.A., A.H.), and INclude Health Data Warehouse (C.G., L.S.), CHU Lille-Université Lille, Rue Emile Laine, 59000 Lille, France; Department of Radiology, UC Davis Health, Sacramento, Calif (L.H.B.); Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France (P.A., A.H.); INSERM, U1172-LilNCog-Lille Neuroscience & Cognition, Université Lille, Lille, France (J.P.P., G.K.); and UAR 2014-US 41-PLBS-Plateformes Lilloises en Biologie & Santé, Université Lille, Lille, France (J.P.P., G.K.).
Lucas ShortenFrom the Department of Neuroradiology (B.L.G., A.L., C.B., J.P.P., G.K.), Department of Public Health (B.L.G., P.A., A.H.), and INclude Health Data Warehouse (C.G., L.S.), CHU Lille-Université Lille, Rue Emile Laine, 59000 Lille, France; Department of Radiology, UC Davis Health, Sacramento, Calif (L.H.B.); Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France (P.A., A.H.); INSERM, U1172-LilNCog-Lille Neuroscience & Cognition, Université Lille, Lille, France (J.P.P., G.K.); and UAR 2014-US 41-PLBS-Plateformes Lilloises en Biologie & Santé, Université Lille, Lille, France (J.P.P., G.K.).ORCID 0009-0003-7748-7582
Cyril BrugeFrom the Department of Neuroradiology (B.L.G., A.L., C.B., J.P.P., G.K.), Department of Public Health (B.L.G., P.A., A.H.), and INclude Health Data Warehouse (C.G., L.S.), CHU Lille-Université Lille, Rue Emile Laine, 59000 Lille, France; Department of Radiology, UC Davis Health, Sacramento, Calif (L.H.B.); Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France (P.A., A.H.); INSERM, U1172-LilNCog-Lille Neuroscience & Cognition, Université Lille, Lille, France (J.P.P., G.K.); and UAR 2014-US 41-PLBS-Plateformes Lilloises en Biologie & Santé, Université Lille, Lille, France (J.P.P., G.K.).
Lotfi Hacein-BeyFrom the Department of Neuroradiology (B.L.G., A.L., C.B., J.P.P., G.K.), Department of Public Health (B.L.G., P.A., A.H.), and INclude Health Data Warehouse (C.G., L.S.), CHU Lille-Université Lille, Rue Emile Laine, 59000 Lille, France; Department of Radiology, UC Davis Health, Sacramento, Calif (L.H.B.); Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France (P.A., A.H.); INSERM, U1172-LilNCog-Lille Neuroscience & Cognition, Université Lille, Lille, France (J.P.P., G.K.); and UAR 2014-US 41-PLBS-Plateformes Lilloises en Biologie & Santé, Université Lille, Lille, France (J.P.P., G.K.).
Philippe AmouyelFrom the Department of Neuroradiology (B.L.G., A.L., C.B., J.P.P., G.K.), Department of Public Health (B.L.G., P.A., A.H.), and INclude Health Data Warehouse (C.G., L.S.), CHU Lille-Université Lille, Rue Emile Laine, 59000 Lille, France; Department of Radiology, UC Davis Health, Sacramento, Calif (L.H.B.); Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France (P.A., A.H.); INSERM, U1172-LilNCog-Lille Neuroscience & Cognition, Université Lille, Lille, France (J.P.P., G.K.); and UAR 2014-US 41-PLBS-Plateformes Lilloises en Biologie & Santé, Université Lille, Lille, France (J.P.P., G.K.).ORCID 0000-0001-9088-234X
Jean-Pierre PruvoFrom the Department of Neuroradiology (B.L.G., A.L., C.B., J.P.P., G.K.), Department of Public Health (B.L.G., P.A., A.H.), and INclude Health Data Warehouse (C.G., L.S.), CHU Lille-Université Lille, Rue Emile Laine, 59000 Lille, France; Department of Radiology, UC Davis Health, Sacramento, Calif (L.H.B.); Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France (P.A., A.H.); INSERM, U1172-LilNCog-Lille Neuroscience & Cognition, Université Lille, Lille, France (J.P.P., G.K.); and UAR 2014-US 41-PLBS-Plateformes Lilloises en Biologie & Santé, Université Lille, Lille, France (J.P.P., G.K.).
Gregory KuchcinskiFrom the Department of Neuroradiology (B.L.G., A.L., C.B., J.P.P., G.K.), Department of Public Health (B.L.G., P.A., A.H.), and INclude Health Data Warehouse (C.G., L.S.), CHU Lille-Université Lille, Rue Emile Laine, 59000 Lille, France; Department of Radiology, UC Davis Health, Sacramento, Calif (L.H.B.); Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France (P.A., A.H.); INSERM, U1172-LilNCog-Lille Neuroscience & Cognition, Université Lille, Lille, France (J.P.P., G.K.); and UAR 2014-US 41-PLBS-Plateformes Lilloises en Biologie & Santé, Université Lille, Lille, France (J.P.P., G.K.).ORCID 0000-0001-8206-198X
Aghiles HamrounFrom the Department of Neuroradiology (B.L.G., A.L., C.B., J.P.P., G.K.), Department of Public Health (B.L.G., P.A., A.H.), and INclude Health Data Warehouse (C.G., L.S.), CHU Lille-Université Lille, Rue Emile Laine, 59000 Lille, France; Department of Radiology, UC Davis Health, Sacramento, Calif (L.H.B.); Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France (P.A., A.H.); INSERM, U1172-LilNCog-Lille Neuroscience & Cognition, Université Lille, Lille, France (J.P.P., G.K.); and UAR 2014-US 41-PLBS-Plateformes Lilloises en Biologie & Santé, Université Lille, Lille, France (J.P.P., G.K.).ORCID 0000-0003-4988-206X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose To assess the performance of a local open-source large language model (LLM) in various information extraction tasks from real-life emergency brain MRI reports. Materials and Methods All consecutive emergency brain MRI reports written in 2022 from a French quaternary center were retrospectively reviewed. Two radiologists identified MRI scans that were performed in the emergency department for headaches. Four radiologists scored the reports' conclusions as either normal or abnormal. Abnormalities were labeled as either headache-causing or incidental. Vicuna (LMSYS Org), an open-source LLM, performed the same tasks. Vicuna's performance metrics were evaluated using the radiologists' consensus as the reference standard. Results Among the 2398 reports during the study period, radiologists identified 595 that included headaches in the indication (median age of patients, 35 years [IQR, 26-51 years]; 68% [403 of 595] women). A positive finding was reported in 227 of 595 (38%) cases, 136 of which could explain the headache. The LLM had a sensitivity of 98.0% (95% CI: 96.5, 99.0) and specificity of 99.3% (95% CI: 98.8, 99.7) for detecting the presence of headache in the clinical context, a sensitivity of 99.4% (95% CI: 98.3, 99.9) and specificity of 98.6% (95% CI: 92.2, 100.0) for the use of contrast medium injection, a sensitivity of 96.0% (95% CI: 92.5, 98.2) and specificity of 98.9% (95% CI: 97.2, 99.7) for study categorization as either normal or abnormal, and a sensitivity of 88.2% (95% CI: 81.6, 93.1) and specificity of 73% (95% CI: 62, 81) for causal inference between MRI findings and headache. Conclusion An open-source LLM was able to extract information from free-text radiology reports with excellent accuracy without requiring further training.

Indexed as

HeadacheMagnetic Resonance ImagingNatural Language ProcessingAdultBrainEmergency Service, HospitalFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityBrainGenerative Pretrained Transformers (GPT)Information ExtractionLarge Language Model (LLM)MRIOpen SourceReport

Identifiers

PMID38717292
PMCPMC11294959

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.