Evidence map›Paper›PMID 38717056›Full record

ArticleImmunity, inflammation and disease2024

The association between enteral nutrition with survival of critical patients with COVID-19.

Maryam Gholamalizadeh, Zahra Salimi, Khadijeh Abbasi Mobarakeh, Zahra Mahmoudi, Shirin Tajadod, Mahdi Mousavi Mele, Farkhondeh Alami, Bojlul Bahar, Saeid Doaei, Sara Khoshdooz and 3 more

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In one paragraph

Article in Immunity, inflammation and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Maryam GholamalizadehCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zahra SalimiStudent Research Committee, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Khadijeh Abbasi MobarakehDepartment of Community Nutrition, Nutrition and Food Security Research Center, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Zahra MahmoudiDepartment of Nutrition, Science and Research Branch Islamic Azad University, Tehran, Iran.
Shirin TajadodDepartment of Nutrition, School of Public Health, International Campus, Iran University of Medical Sciences, Tehran, Iran.
Mahdi Mousavi MeleDepartment of Nutrition, University of Medical Sciences, Tehran, Iran.
Farkhondeh AlamiNutrition Sciences and Applied Food Safety Studies, Research Centre for Global Development, School of Sport and Health Sciences, University of Central Lancashire, Preston, UK.
Bojlul BaharDepartment of Nutrition, Student Research Committee, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Saeid DoaeiCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sara KhoshdoozRazi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.ORCID 0000-0001-9872-7993
Masoume RahvarIntensive Care Unit (ICU), Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Somayeh GholamiIntensive Care Unit (ICU), Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Masoume PourtalebIntensive Care Unit (ICU), Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.

Funding

Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 43005810
6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) results in several complications and mortality in intensive care unit (ICU) patients. Limited studies have investigated the effect of enteral nutrition (EN) on the survival of COVID-19 patients in the ICU. The aim of this study was to investigate the association of EN with biochemical and pathological indices associated with mortality in ICU patients with COVID-19.

methodsThis case-control study was conducted on 240 patients with COVID-19 hospitalized in the ICU including 120 eventual nonsurvived as the cases and 120 survived patients as the controls. All of the patients received EN as a high protein high volume or standard formula. Data on general information, anthropometric measurements, and the results of lab tests were collected.

resultsThe recovered patients received significantly more high protein (60.8% vs. 39.6%, p = .004) and high volume (61.6% vs. 42.3%, p = .005) formula compared to the nonsurvived group. Mortality was inversely associated with high volume (odds ratio [OR]: 0.45 confidence interval [CI]95%, p = .008) and high protein (OR: 0.42 CI95%, p = .003) formula. The results remained significant after adjusting for age and sex. Further adjustment for underlying diseases, smoking, body mass index, and the acute physiology and chronic health evaluation II (APACHE II) score did not change the results.

conclusionThe findings of the study showed that there was a significant inverse association between mortality and high volume and high protein formula in patients with COVID-19. Further investigation is warranted.

Indexed as

COVID-19Enteral NutritionIntensive Care UnitsSARS-CoV-2AdultAgedCase-Control StudiesCritical IllnessFemaleHumansMaleMiddle AgedCOVID‐19enteral nutritionmortalitysurvival

Identifiers

PMID38717056
PMCPMC11078021

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.