Evidence map›Paper›PMID 38716984›Full record

ArticleBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2024

Crescentic glomerulonephritis due to linear IgA anti-glomerular basement membrane disease: report of a rare case.

A G Monich, R F Romani, J L S Carneiro

Abstract readCase Reports
In one paragraph

Article in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A G MonichServiço de Nefrologia, Hospital Universitário Evangélico Mackenzie, Curitiba, PR, Brasil.ORCID http://orcid.org/0000-0002-7256-6674
R F RomaniServiço de Nefrologia, Hospital Universitário Evangélico Mackenzie, Curitiba, PR, Brasil.ORCID http://orcid.org/0000-0002-8926-2837
J L S CarneiroServiço de Nefrologia, Hospital Universitário Evangélico Mackenzie, Curitiba, PR, Brasil.ORCID http://orcid.org/0000-0003-4160-1040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-glomerular basement membrane (GBM) disease is a rare and severe vasculitis that affects the glomerular and pulmonary capillaries and has an incidence of less than 2 cases per million individuals per year. Anti-GBM disease is mediated by autoantibodies against the α3 chain of type IV collagen. In the majority of cases, the autoantibodies are of the immunoglobulin G (IgG) class, with rare cases being mediated by immunoglobulin M (IgM) or immunoglobulin A (IgA); there are less than 15 IgA-mediated cases reported in the literature worldwide. The classic form of this disease manifests with rapidly progressive glomerulonephritis (RPGN), with or without pulmonary hemorrhage, and the diagnosis consists of identifying high titers of autoantibodies in the serum and/or deposited in the tissues. IgA antibodies are not identified in routine immunoassay tests, and renal biopsy with immunofluorescence is essential for diagnosis. We present a case of RPGN due to anti-GBM disease with linear IgA deposition, whose diagnosis was made exclusively by renal biopsy and with an unfavorable prognosis.

Indexed as

Anti-Glomerular Basement Membrane DiseaseAutoantibodiesGlomerulonephritisImmunoglobulin ABiopsyFemaleHumansMaleAutoantibodiesImmunoglobulin A

Identifiers

PMID38716984
PMCPMC11085031

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.